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1. (WO2007002081) GFATS AS MODIFIERS OF THE AXIN PATHWAY AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/002081    International Application No.:    PCT/US2006/023971
Publication Date: 04.01.2007 International Filing Date: 20.06.2006
IPC:
C12Q 1/68 (2006.01), G01N 33/00 (2006.01), G01N 33/53 (2006.01), C12N 15/00 (2006.01), A01N 61/00 (2006.01), A01N 31/00 (2006.01)
Applicants: EXELIXIS, INC. [US/US]; 170 Harbor Way, P.O. Box 511, South San Francisco, CA 94083-0511 (US) (For All Designated States Except US).
GENDREAU, Steven, Brian [US/US]; (US) (For US Only).
DORA, Emery, G.III [US/US]; (US) (For US Only).
LICKTEIG, Kim [US/US]; (US) (For US Only)
Inventors: GENDREAU, Steven, Brian; (US).
DORA, Emery, G.III; (US).
LICKTEIG, Kim; (US)
Agent: SEPERACK, Peter, K.; EXELIXIS, INC., 170 Harbor Way, P.O. Box 511, South San Francisco, CA 94083-0511 (US)
Priority Data:
60/692,316 20.06.2005 US
Title (EN) GFATS AS MODIFIERS OF THE AXIN PATHWAY AND METHODS OF USE
(FR) GFATS UTILISES COMME MODIFICATEURS DE LA VOIE DE L AXINE ET LEURS PROCEDES D'UTILISATION
Abstract: front page image
(EN)Human GFAT genes are identified as modulators of the Axin pathway, and thus are therapeutic targets for disorders associated with defective Axin function. Methods for identifying modulators of Axin, comprising screening for agents that modulate the activity of GFAT are provided.
(FR)Les gènes GFAT humains sont identifiés comme modulateurs de la voie de l'axine, et sont ainsi des cibles thérapeutiques de troubles liés à une fonction défectueuse de l'axine. L'invention concerne également des procédés d'identification de modulateurs de l'axine, comportant le criblage d'agents qui modulent l'activité de GFAT .
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)