Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2007001406) ARYL-CONTAINING MACROCYCLIC COMPOUNDS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/001406 International Application No.: PCT/US2005/035853
Publication Date: 04.01.2007 International Filing Date: 05.10.2005
IPC:
A61K 38/00 (2006.01) ,C07K 5/083 (2006.01) ,C12P 17/08 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
5
Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04
containing only normal peptide links
08
Tripeptides
083
the side chain of the first amino acid being acyclic, e.g. Gly, Ala
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
17
Preparation of heterocyclic carbon compounds with only O, N, S, Se, or Te as ring hetero atoms
02
Oxygen as only ring hetero atoms
08
containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
Applicants:
CHIRON CORPORATION [US/US]; 4560 Horton Street Emeryville, CA 94608-2916, US (AllExceptUS)
BURGER, Matthew, T. [US/US]; US (UsOnly)
BUSSIERE, Dirksen [US/US]; US (UsOnly)
MURRAY, Jeremy [US/US]; US (UsOnly)
NG, Simon [GB/US]; US (UsOnly)
NI, Zhi-Jie [US/US]; US (UsOnly)
PFISTER, Keith, B. [US/US]; US (UsOnly)
WAGMAN, Allan, S. [US/US]; US (UsOnly)
ZHOU, Yasheen [CN/US]; US (UsOnly)
Inventors:
BURGER, Matthew, T.; US
BUSSIERE, Dirksen; US
MURRAY, Jeremy; US
NG, Simon; US
NI, Zhi-Jie; US
PFISTER, Keith, B.; US
WAGMAN, Allan, S.; US
ZHOU, Yasheen; US
Agent:
HSI, Jeffrey, D. ; Edwards Angell Palmer & Dodge LLP P.O. Box 55874 Boston, MA 02205, US
Priority Data:
60/616,42105.10.2004US
Title (EN) ARYL-CONTAINING MACROCYCLIC COMPOUNDS
(FR) COMPOSES MACROCYCLIQUES CONTENANT UN ARYLE
Abstract:
(EN) The present invention discloses novel compounds, compositions containing the compounds and methods for the treatment of viral infection, particularly hepatitis C and SARS. In particular the invention provides aryl-containing macrocyclic compounds useful for the inhibition of HCV and SARS viral replication.
(FR) La présente invention concerne des nouveaux composés, des compositions contenant lesdits composés et des méthodes de traitement d'une infection virale, notamment, de l'hépatite C et du SARS. Plus spécifiquement, cette invention a pour objet des composés macrocycliques contenant un aryle utilisés dans l'inhibition de la réplication virale du VHC et du SARS.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)