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1. (WO2007000979) SELF-ASSEMBLING PEPTIDE AND GEL PRODUCED FROM THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/000979    International Application No.:    PCT/JP2006/312729
Publication Date: 04.01.2007 International Filing Date: 26.06.2006
Chapter 2 Demand Filed:    23.04.2007    
IPC:
C07K 7/08 (2006.01), A61L 27/00 (2006.01), C09K 3/00 (2006.01)
Applicants: Menicon Co., Ltd. [JP/JP]; 21-19, Aoi 3-chome, Naka-ku, Nagoya-shi, Aichi 4600006 (JP) (For All Designated States Except US).
Nagoya Institute of Technology [JP/JP]; Gokiso-cho, Showa-ku, Nagoya-shi, Aichi 4668555 (JP) (For All Designated States Except US).
YOKOI, Hidenori; (For US Only).
KINOSHITA, Takatoshi; (For US Only)
Inventors: YOKOI, Hidenori; .
KINOSHITA, Takatoshi;
Agent: HOSODA, Yoshinori; c/o Hosoda International Patent Office P.O. Box 26, OMM Building 5th Floor 7-31, Otemae 1-chome Chuo-ku, Osaka-shi, Osaka 5406591 (JP)
Priority Data:
2005-186573 27.06.2005 JP
Title (EN) SELF-ASSEMBLING PEPTIDE AND GEL PRODUCED FROM THE SAME
(FR) PEPTIDE AUTO-ASSEMBLE ET GEL FABRIQUE A PARTIR DE CE PEPTIDE
(JA) 自己組織化ペプチドおよびそれより得られるゲル
Abstract: front page image
(EN)A self-assembling peptide having a polar amino acid residue and a non-polar amino acid residue, the polar amino acid residue comprising an acidic amino acid residue and a basic amino acid residue, the sum of the amount of charge of the acidic amino acid residue and the amount of charge of the basic amino acid residue being not 0 in the neutral range, and the peptide being capable of forming a &bgr;-sheet structure only having the non-polar amino acid residue arranged on one side of the &bgr;-sheet structure when self-assembled in an aqueous solution.
(FR)L'invention concerne un peptide auto-assemblé comportant un résidu d'acide aminé polaire et un résidu d'acide aminé non polaire, le résidu d'acide aminé polaire comprenant un résidu d'acide aminé acide et un résidu d'acide aminé basique, la somme des charges du résidu d'acide aminé acide et des charges du résidu d'acide aminé basique n'étant pas égale à 0 dans la gamme neutre, et le peptide étant capable de former une structure de feuillet bêta ne comportant que le résidu d'acide aminé non polaire disposé sur une face de la structure en feuillet bêta, lorsque le peptide est auto-assemblé en solution aqueuse.
(JA) 極性アミノ酸残基と非極性アミノ酸残基とを有する自己組織化ペプチドであって、 該極性アミノ酸残基として酸性アミノ酸残基及び塩基性アミノ酸残基を含み、 中性領域において、該酸性アミノ酸残基の電荷と該塩基性アミノ酸残基の電荷との総和が0を除く数であり、水溶液中において自己組織化した際に該非極性アミノ酸残基のみが一方の面に配置されたβ-シート構造を形成しうる自己組織化ペプチド。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)