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1. (WO2007000337) BICYCLIC DERIVATIVES AS P38 KINASE INHIBITORS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2007/000337 International Application No.: PCT/EP2006/006253
Publication Date: 04.01.2007 International Filing Date: 28.06.2006
IPC:
C07D 209/46 (2006.01) ,C07C 233/65 (2006.01) ,A61K 31/4035 (2006.01) ,A61K 31/165 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
209
Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
02
condensed with one carbocyclic ring
44
Iso-indoles; Hydrogenated iso-indoles
46
with an oxygen atom in position 1
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
233
Carboxylic acid amides
64
having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
65
having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
40
having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403
condensed with carbocyclic rings, e.g. carbazole
4035
Isoindoles, e.g. phthalimide
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
16
Amides, e.g. hydroxamic acids
165
having aromatic rings, e.g. colchicine, atenolol, progabide
Applicants:
PALAU PHARMA, S.A. [ES/ES]; Avinguda Camí Reial, 51-57 Pol. Ind. Riera de Caldes E-08184 Palau-solità i Plegamans, ES (AllExceptUS)
ALMANSA ROSALES, Carmen [ES/ES]; ES (UsOnly)
VIRGILI BERNADÓ, Marina [ES/ES]; ES (UsOnly)
Inventors:
ALMANSA ROSALES, Carmen; ES
VIRGILI BERNADÓ, Marina; ES
Agent:
ZUMSTEIN, F.; Pfenning, Meinig & Partner GbR Theresienhöhe 13 80339 München, DE
Priority Data:
05380142.929.06.2005EP
Title (EN) BICYCLIC DERIVATIVES AS P38 KINASE INHIBITORS
(FR) DERIVES BICYCLIQUES UTILISES EN TANT QU'INHIBITEURS DE P38 KINASE
Abstract:
(EN) New bicyclic derivatives of formula (I); wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as p38 kinase inhibitors.
(FR) L'invention se rapporte à de nouveaux dérivés bicycliques de formule (I), dans laquelle les significations des différents substituants sont précisées dans la description. Ces composés sont utiles en tant qu'inhibiteurs de p38 kinase.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)