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Machine translation
1. (WO2007000328) ANTIBODIES THAT BIND TO AN EPITOPE ON INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/000328    International Application No.:    PCT/EP2006/006221
Publication Date: 04.01.2007 International Filing Date: 26.06.2006
IPC:
C07K 16/28 (2006.01), A61K 39/395 (2006.01), C12N 5/20 (2006.01), C12N 15/63 (2006.01), A61P 35/00 (2006.01)
Applicants: ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA [IT/IT]; Via Pontina KM 30.600, I-00040 Pomezia (IT) (For All Designated States Except US).
PIERRE FABRE MEDICAMENT [FR/FR]; 45 Place Abel Gance, F-92100 Boulogne (FR) (For All Designated States Except US).
HAEUW, Jean-Francois [FR/FR]; (FR) (For US Only).
KLINGUER-HAMOUR, Christine [FR/FR]; (FR) (For US Only).
PESSI, Antonello [IT/IT]; (IT) (For US Only).
TALAMO, Fabio [IT/IT]; (IT) (For US Only)
Inventors: HAEUW, Jean-Francois; (FR).
KLINGUER-HAMOUR, Christine; (FR).
PESSI, Antonello; (IT).
TALAMO, Fabio; (IT)
Agent: BUCHAN, Gavin, MacNicol; Merck Sharp & Dohme Limited, European Patent Department, Hertford Road, Hoddesdon, Hertfordshire EN11 9BU (GB)
Priority Data:
60/694,802 27.06.2005 US
60/700,110 18.07.2005 US
Title (EN) ANTIBODIES THAT BIND TO AN EPITOPE ON INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR AND USES THEREOF
(FR) ANTICORPS SE FIXANT À UN ÉPITOPE SUR UN RÉCEPTEUR DE FACTEUR DE CROISSANCE INSULINOMIMÉTIQUE DE TYPE 1 ET LEURS UTILISATIONS
Abstract: front page image
(EN)The invention relates to the identification of an epitopic region within the extracellular domain of human IGF-1 receptor. Methods of identifying antibodies that specifically bind to the herein disclosed epitopic region together with compositions comprising the antibodies and uses thereof in treating IGF-1 receptor mediated disorders, particularly those that over express IGF-1 receptor are disclosed.
(FR)L’invention concerne l’identification d’une région épitope à l’intérieur du domaine extracellulaire du récepteur humain IGF-1. L’invention concerne également des procédés permettant d’identifier des anticorps qui se fixent spécifiquement à la région épitope présentée ici avec des compositions comprenant les anticorps, et leurs utilisations dans le traitement des troubles induits par le récepteur IGF-1, en particulier ceux qui sur-expriment le récepteur IGF-1
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)