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Machine translation
1. (WO2007000292) NOVEL TARGETS AND COMPOUNDS USEFUL IN THE TREATMENT AND/OR PROPHYLAXIS OF A CARDIOVASCULAR DISORDER, DYSLIPIDEMIA AND ATHEROSCLEROSIS, AND METHODS TO IDENTIFY SUCH COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2007/000292    International Application No.:    PCT/EP2006/006117
Publication Date: 04.01.2007 International Filing Date: 24.06.2006
IPC:
C12Q 1/48 (2006.01), A61K 48/00 (2006.01), A61P 3/00 (2006.01), A61P 9/00 (2006.01)
Applicants: GALAPAGOS NV [BE/BE]; Industriepark Mechelen Noord, Generaal De Wittelaan L11 A 3, B-2800 Mechelen (BE) (For All Designated States Except US).
BETZ, Ulrich [DE/DE]; (DE) (For US Only).
D'URSO, Donatella [IT/DE]; (DE) (For US Only).
GATSIOS, Petros [GR/DE]; (DE) (For US Only).
SEEWALD, Michael [DE/DE]; (DE) (For US Only).
STRAYLE, Jochen [DE/DE]; (DE) (For US Only).
VAN ES, Helmuth, Hendrikus, Gerardus [NL/NL]; (NL) (For US Only).
VAN ZUTPHEN, Marlijn [NL/NL]; (NL) (For US Only).
MESIC, Emir [NL/NL]; (NL) (For US Only)
Inventors: BETZ, Ulrich; (DE).
D'URSO, Donatella; (DE).
GATSIOS, Petros; (DE).
SEEWALD, Michael; (DE).
STRAYLE, Jochen; (DE).
VAN ES, Helmuth, Hendrikus, Gerardus; (NL).
VAN ZUTPHEN, Marlijn; (NL).
MESIC, Emir; (NL)
Agent: MANTEN, Annemieke; Arnold & Siedsma, Sweelinckplein 1, NL-2517 GK The Hague (NL)
Priority Data:
60/695,649 29.06.2005 US
Title (EN) NOVEL TARGETS AND COMPOUNDS USEFUL IN THE TREATMENT AND/OR PROPHYLAXIS OF A CARDIOVASCULAR DISORDER, DYSLIPIDEMIA AND ATHEROSCLEROSIS, AND METHODS TO IDENTIFY SUCH COMPOUNDS
(FR) NOUVELLES CIBLES ET COMPOSES UTILES POUR LE TRAITEMENT ET/OU LA PROPHYLAXIE DE TROUBLES CARDIO-VASCULAIRES DE LA DISLIPIDEMIE, ET DE L'ATHEROSCLEROSE, ET PROCEDES D'IDENTIFICATION DE TELS COMPOSES
Abstract: front page image
(EN)The present invention provides targets and methods for the screening for compounds useful in the prevention, amelioration or treatment and/or prophylaxis of a cardiovascular disorder, dyslipidemia, and/or Atherosclerosis. The invention also relates to the targets that were identified. Inhibiting or activating target genes of the invention, or their expression products, by using compounds identifiable by methods of the invention, is beneficial in the treatment and/or prophylaxis of diseases involving a cardiovascular disorder, dyslipidemia, and/or Atherosclerosis.
(FR)L'invention porte sur des cibles et méthodes utiles pour le criblage de composés utiles pour la prévention, l'amélioration, le traitement et/ou la prophylaxie de troubles cardio-vasculaires, de la dyslipidémie, et/ou de l'athérosclérose. L'invention porte également sur les cibles ainsi identifiées. L'inhibition ou l'activation de gènes cibles ou de leurs produits d'expression au moyen des composés identifiables par les procédés de l'invention s'avère en effet bénéfique pour le traitement et/ou la prophylaxie de tels troubles et maladies.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)