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1. (WO2006128125) METHODS OF AND COMPOSITIONS FOR STIMULATION OF GLUCOSE UPTAKE INTO MUSCLE CELLS AND TREATMENT OF DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/128125    International Application No.:    PCT/US2006/020797
Publication Date: 30.11.2006 International Filing Date: 30.05.2006
IPC:
A61K 38/20 (2006.01)
Applicants: FIVE PRIME THERAPEUTICS, INC. [US/US]; 1650 Owens Street, Suite 200, San Francisco, CA 94158-2261 (US) (For All Designated States Except US).
LIN, Junyu [CN/US]; (US) (For US Only).
KOTHAKOTA, Srinivas [IN/US]; (US) (For US Only).
WU, Ge [US/US]; (US) (For US Only).
DOBERSTEIN, Stephen [US/US]; (US) (For US Only).
BRENNAN, Thomas [US/US]; (US) (For US Only).
MASUOKA, Lorianne [US/US]; (US) (For US Only).
QIN, Minmin [US/US]; (US) (For US Only).
MARSHALL, Shannon [US/US]; (US) (For US Only).
WANG, Yan [CN/US]; (US) (For US Only).
HOLLENBAUGH, Diane [US/US]; (US) (For US Only).
WILLIAMS, Lewis, T. [US/US]; (US) (For US Only)
Inventors: LIN, Junyu; (US).
KOTHAKOTA, Srinivas; (US).
WU, Ge; (US).
DOBERSTEIN, Stephen; (US).
BRENNAN, Thomas; (US).
MASUOKA, Lorianne; (US).
QIN, Minmin; (US).
MARSHALL, Shannon; (US).
WANG, Yan; (US).
HOLLENBAUGH, Diane; (US).
WILLIAMS, Lewis, T.; (US)
Agent: GARRETT, Arthur, S.; Finnegan, Henderson, Farabow, Garrett, and Dunner L.L.P., 901 New York Avenue, Nw, Washington, DC 20001-4413 (US)
Priority Data:
60/685,702 27.05.2005 US
60/701,490 22.07.2005 US
60/701,964 22.07.2005 US
60/702,065 22.07.2005 US
60/733,791 07.11.2005 US
60/736,866 16.11.2005 US
60/778,169 27.02.2006 US
60/800,443 16.05.2006 US
11/442,244 30.05.2006 US
Title (EN) METHODS OF AND COMPOSITIONS FOR STIMULATION OF GLUCOSE UPTAKE INTO MUSCLE CELLS AND TREATMENT OF DISEASES
(FR) METHODES ET COMPOSITIONS POUR STIMULER LE CAPTAGE DU GLUCOSE DANS DES CELLULES MUSCULAIRES ET POUR TRAITER DES MALADIES
Abstract: front page image
(EN)The present invention relates to therapeutic uses of ErbB ligands, including betacellulin. The therapeutic uses include methods of using ErbB ligand family compounds alone, or in conjunction with other agents, for reducing blood glucose levels, treating Type I and Type II diabetes, obesity, muscle wasting diseases, and cardiotoxicity.
(FR)L'invention concerne des utilisations thérapeutiques de ligands ErbB contenant de la bêtacelluline. Ces utilisations thérapeutiques comprennent des méthodes d'utilisation de composés de la famille des ligands ErbB seuls, ou combinés à d'autres agents, pour réduire des taux de glycémie, pour traiter des diabètes de type I et de type II, l'obésité, des maladies amyotrophiques et une cardiotoxicité.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)