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Machine translation
1. (WO2006127550) PROLINE BIS-AMIDE OREXIN RECEPTOR ANTAGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/127550    International Application No.:    PCT/US2006/019649
Publication Date: 30.11.2006 International Filing Date: 22.05.2006
IPC:
C07D 403/12 (2006.01)
Applicants: MERCK & CO., INC. [US/US]; 126 East Lincoln Avenue, Rahway, New Jersey 07065-0907 (US) (For All Designated States Except US).
BERGMAN, Jeffrey, M. [US/US]; (US) (For US Only).
COLEMAN, Paul, J. [US/US]; (US) (For US Only).
COX, Christopher [US/US]; (US) (For US Only).
HARTMAN, George, D. [US/US]; (US) (For US Only).
LINDSLEY, Craig [US/US]; (US) (For US Only).
MERCER, Swati Pal [US/US]; (US) (For US Only).
ROECKER, Anthony, J. [US/US]; (US) (For US Only).
WHITMAN, David, B. [US/US]; (US) (For US Only)
Inventors: BERGMAN, Jeffrey, M.; (US).
COLEMAN, Paul, J.; (US).
COX, Christopher; (US).
HARTMAN, George, D.; (US).
LINDSLEY, Craig; (US).
MERCER, Swati Pal; (US).
ROECKER, Anthony, J.; (US).
WHITMAN, David, B.; (US)
Common
Representative:
MERCK & CO., INC.; 126 East Lincoln Avenue, Rahway, New Jersey 07065-0907 (US)
Priority Data:
60/683,690 23.05.2005 US
Title (EN) PROLINE BIS-AMIDE OREXIN RECEPTOR ANTAGONISTS
(FR) ANTAGONISTES DES RECEPTEURS D'OREXINE A BASE DE BIS-AMIDE DE PROLINE
Abstract: front page image
(EN)The present invention is directed to proline bis-amide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
(FR)La présente invention concerne des composés bis-amide de proline qui sont des antagonistes des récepteurs d'orexine, et qui sont utiles dans le traitement ou la prévention de troubles et de maladies neurologiques et psychiatriques impliquant les récepteurs d'orexine. L'invention concerne également des compositions pharmaceutiques comprenant ces composés, ainsi que l'utilisation de ces composés et compositions dans la prévention ou le traitement de telles maladies impliquant les récepteurs d'orexine.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)