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1. (WO2006127009) REAGENT FOR THE IMPROVED SYNTHESIS OF ISOGUANOSINE-CONTAINING OLIGONUCLEOTIDES

Pub. No.:    WO/2006/127009    International Application No.:    PCT/US2005/018680
Publication Date: Nov 30, 2006 International Filing Date: May 26, 2005
IPC: C07H 19/167
C07H 19/173
Applicants: ERAGEN BIOSCIENCES, INC.
PRUDENT, James, R.
SHERRILL, Christopher, B.
Inventors: PRUDENT, James, R.
SHERRILL, Christopher, B.
Title: REAGENT FOR THE IMPROVED SYNTHESIS OF ISOGUANOSINE-CONTAINING OLIGONUCLEOTIDES
Abstract:
The present invention provides the combination of the O-2 diphenylcarbamoyl ('DPC') and N-6 dimethylaminomethylidene ('DMF') protecting groups for isoguanosine nucleosides that can be utilized in oligonucleotide synthesis.