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1. (WO2006126198) ARTS C-TERMINUS FRAGMENTS AND MIMETICS THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/126198    International Application No.:    PCT/IL2006/000613
Publication Date: 30.11.2006 International Filing Date: 24.05.2006
IPC:
C07K 5/00 (2006.01), C07K 7/00 (2006.01), A61K 38/00 (2006.01), G01N 33/53 (2006.01)
Applicants: SIMETRA PHARM LTD. [IL/IL]; P.o.box 408, South Industrial Area, 11013 Kiryat Shmona (IL) (For All Designated States Except US).
LARISCH, Sarit [IL/IL]; (IL) (For US Only)
Inventors: LARISCH, Sarit; (IL)
Agent: PEARL COHEN ZEDEK LATZER; 5 Shenkar Street, P.o.box 12704, 46733 Herzlia (IL)
Priority Data:
60/684,174 25.05.2005 US
Title (EN) ARTS C-TERMINUS FRAGMENTS AND MIMETICS THEREOF
(FR) FRAGMENTS DE TERMINUS C DE MOLECULE ARTS T MIMETIQUES
Abstract: front page image
(EN)This invention provides isolated peptides comprising a C-terminal fragment of an ARTS protein, isolated nucleotides encoding same, mimetics and small molecule analogues of same, and therapeutic applications comprising administering a peptide, nucleic acid, or mimetic compound of the present invention. This invention also provides isolated complexes comprising a C-terminal fragment of an ARTS protein and either an IAP protein, a Bir3 domain thereof, or a fragment thereof; compounds that bind or interact with same, and use of the compounds in therapeutic applications.
(FR)Cette invention concerne des peptides isolé contenant des fragments de terminus C d'une protéine ARTS, des nucléotides isolés codant pour cette protéine, des mimétiques et des analogues de petite molécule, ainsi que des applications thérapeutiques consistant à administrer un peptide, un acide nucléique ou un composé mimétique de l'invention. De plus, cette invention porte sur des complexes isolés comprenant un fragment de terminus C d'une protéine ARTS et soit une protéine IAP, un domaine Bir3, ou un fragment de cette protéine, ainsi que des composés se liant à cette protéine ou interagissant avec celle-ci, et l'utilisation de ces composés à des fins thérapeutiques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)