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1. WO2006125815 - TETRAHYDROPYRIDOTHIOPHENES FOR USE IN THE TREATMENT OF CANCER

Publication Number WO/2006/125815
Publication Date 30.11.2006
International Application No. PCT/EP2006/062617
International Filing Date 24.05.2006
IPC
C07D 495/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
495Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
A61K 31/4365 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
4353ortho- or peri-condensed with heterocyclic ring systems
4365the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
A61P 35/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61P 31/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
18for HIV
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
C07D 495/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
495Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants
  • NYCOMED GMBH [DE]/[DE] (AllExceptUS)
  • PEKARI, Klaus [DE]/[DE] (UsOnly)
  • SCHMIDT, Mathias [DE]/[DE] (UsOnly)
  • BÄR, Thomas [DE]/[DE] (UsOnly)
  • BECKERS, Thomas [DE]/[DE] (UsOnly)
  • GIMMNICH, Petra [DE]/[DE] (UsOnly)
Inventors
  • PEKARI, Klaus
  • SCHMIDT, Mathias
  • BÄR, Thomas
  • BECKERS, Thomas
  • GIMMNICH, Petra
Agents
  • WILD, Robert
Priority Data
05104495.625.05.2005EP
05112155.614.12.2005EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) TETRAHYDROPYRIDOTHIOPHENES FOR USE IN THE TREATMENT OF CANCER
(FR) NOUVEAU TETRAHYDROPYRIDOTHIOPHENES
Abstract
(EN) Compounds of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.
(FR) L'invention concerne des composés d'une certaine formule (I), dans laquelle Ra et Rb ont les significations indiquées dans la description. Ils représentent de nouveaux composés efficaces à activité antiprolifératives et induisant l'apoptose.
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