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1. (WO2006124737) MOLECULAR CONSTRUCTS SUITABLE FOR TARGETED CONJUGATES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/124737    International Application No.:    PCT/US2006/018654
Publication Date: 23.11.2006 International Filing Date: 11.05.2006
IPC:
A61K 47/48 (2006.01)
Applicants: TAPESTRY PHARMACEUTICALS, INC. [US/US]; 4840 Pearl East Circle, Suite 300W Boulder, CO 80301 (US) (For All Designated States Except US).
HENRI, John [US/US]; (US) (For US Only).
MCCHESNEY, James [US/US]; (US) (For US Only).
LAMB, Rodger [US/US]; (US) (For US Only).
VENKATARAMAN, Sylesh [IN/US]; (US) (For US Only)
Inventors: HENRI, John; (US).
MCCHESNEY, James; (US).
LAMB, Rodger; (US).
VENKATARAMAN, Sylesh; (US)
Agent: NGUYEN, Sam, L.; Heller Ehrman LLP, 275 Middlefield Road, Menlo Park, CA 94025 (US)
Priority Data:
60/680,623 12.05.2005 US
Title (EN) MOLECULAR CONSTRUCTS SUITABLE FOR TARGETED CONJUGATES
(FR) PRODUITS DE SYNTHESE MOLECULAIRES ADAPTES A DES CONJUGUES CIBLES
Abstract: front page image
(EN)The present invention relates generally to effective drug-linker constructs suitable for conjugation with ligands. The present invention also discloses methods of conjugating these constructs with peptides to form the compound of formula I. These methods are readily extended to any hydroxyl, amine or sulfur bearing biologically active molecules.
(FR)Cette invention concerne de façon générale des produits de synthèse entre segments de liaison et médicaments, qui sont efficaces et qui sont conçus pour être conjugués avec des ligands. Cette invention concerne également des procédés pour conjuguer ces produits de synthèse avec des peptides pour former le composé représenté par la formule (I). Ces procédés peuvent facilement s'étendre à n'importe quel groupe hydroxyle, amine ou soufre portant des molécules biologiquement actives.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)