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1. (WO2006124000) ALDEHYDE CONJUGATED FLAVONOID PREPARATIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/124000    International Application No.:    PCT/SG2006/000045
Publication Date: 23.11.2006 International Filing Date: 07.03.2006
IPC:
C08B 37/08 (2006.01), A61K 47/48 (2006.01), A61K 31/353 (2006.01), C08G 65/331 (2006.01)
Applicants: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH [SG/SG]; 20 Biopolis Way, #07-01 Centros, Singapore 138668 (SG) (For All Designated States Except US).
ZHUO, Lang [US/SG]; (SG) (For US Only).
CHUNG, Joo Eun [KR/SG]; (SG) (For US Only).
KURISAWA, Motoichi [JP/SG]; (SG) (For US Only).
YANG, Yi Yan [SG/SG]; (SG) (For US Only)
Inventors: ZHUO, Lang; (SG).
CHUNG, Joo Eun; (SG).
KURISAWA, Motoichi; (SG).
YANG, Yi Yan; (SG)
Agent: YU SARN AUDREY & PARTNERS; 190 Middle Road, #12-04, Singapore 188979 (SG)
Priority Data:
60/682,801 20.05.2005 US
Title (EN) ALDEHYDE CONJUGATED FLAVONOID PREPARATIONS
(FR) PREPARATIONS DE FLAVONOIDES CONJUGUES A DES ALDEHYDES
Abstract: front page image
(EN)There is provided a method of conjugating a polymer containing a free aldehyde group with a flavonoid in the presence of an acid catalyst, such that the polymer is conjugated to the C6 or C8 position of the flavonoid A ring. The resulting conjugates may be used to form delivery vehicles to deliver high doses of flavonoids, and may also be used as delivery vehicles to deliver an additional bioactive agent.
(FR)La présente invention concerne une méthode de conjugaison d'un polymère contenant un groupement aldéhyde libre avec un flavonoïde en présence d'un catalyseur acide, de façon à ce que le polymère soit conjugué à la position C6 ou C8 du cycle A du flavonoïde. Les substances conjuguées résultantes peuvent être employées pour élaborer des vecteurs permettant la libération de doses élevées de flavonoïdes, et peuvent également être employées en tant que vecteurs pour la libération d'un agent bioactif supplémentaire.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)