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Machine translation
1. (WO2006123359) A PROCESS OF MAKING MICROSPHERES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/123359    International Application No.:    PCT/IN2006/000065
Publication Date: 23.11.2006 International Filing Date: 01.03.2006
Chapter 2 Demand Filed:    23.09.2006    
IPC:
A61K 9/16 (2006.01)
Applicants: SUN PHARMACEUTICAL INDUSTRIES LIMITED [IN/IN]; ACME PLAZA, Andheri-kurla Road, Andheri (e), Mumbai 400 059 (IN) (For All Designated States Except US).
KHOPADE, Ajay [IN/IN]; (IN) (For US Only).
GEORGE, Alex [IN/IN]; (IN) (For US Only).
BHOWMICK, Subhas Balaram [IN/IN]; (IN) (For US Only)
Inventors: KHOPADE, Ajay; (IN).
GEORGE, Alex; (IN).
BHOWMICK, Subhas Balaram; (IN)
Priority Data:
231/MUM/2005 01.03.2005 IN
1182/MUM/2005 26.09.2005 IN
Title (EN) A PROCESS OF MAKING MICROSPHERES
(FR) PROCEDE DE FABRICATION DE MICROSPHERES OU MICROCAPSULES
Abstract: front page image
(EN)A process for the manufacture of free-flowing uniformly sized microspheres for the sustained release of therapeutically active ingredient comprising: a) preparing a first dispersed phase comprising a therapeutically active ingredient, a biodegradable polymer and an organic solvent; b) mixing the first dispersed phase with a aqueous phase to form an emulsion; c) spraying the emulsion into a vessel (20) equipped with organic solvent removal means; d) passing the suspension of microspheres through screens and collecting a fractionated size of the microspheres on the surface of the screens; e) drying the microspheres wherein steps a to e are carried out without manual intervention, in equipment connected in series, substantially unexposed to the environment;
(FR)Procédé de fabrication de microsphères de taille uniforme à écoulement libre pour la libération prolongée de principe thérapeutiquement actif : a. élaboration de première phase dispersée comprenant ledit principe, un polymère biodégradable et un solvant organique ; b. mélange de cette phase avec une phase aqueuse pour former une émulsion; c. pulvérisation de l'émulsion dans un récipient à système d'élimination de solvant organique ; d. filtrage de la suspension de microsphères ou microcapsules dans des filtres et collecte de taille fractionnée de ces microsphères ou microcapsules à la surface des filtres ; e. séchage final et les étapes a à e sont conduites sans intervention manuelle, dans un équipement relié en série, sensiblement à l'abri de l'environnement.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)