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1. (WO2006121104) CRYSTAL OF INDOLE DERIVATIVE HAVING PIPERIDINE RING AND PROCESS FOR PRODUCTION THEREOF

Pub. No.:    WO/2006/121104    International Application No.:    PCT/JP2006/309459
Publication Date: Nov 16, 2006 International Filing Date: May 11, 2006
IPC: C07D 405/14
A61K 31/454
A61P 1/08
A61P 1/14
A61P 7/10
A61P 7/12
A61P 13/00
A61P 15/00
A61P 25/06
A61P 25/18
A61P 25/20
A61P 25/22
A61P 25/28
A61P 25/30
A61P 25/34
A61P 29/00
A61P 43/00
Applicants: EISAI R & D MANAGEMENT CO., LTD.
エーザイ・アール・アンド・ディー・マネジメント株式会社
SAKAGUCHI, Takahisa
坂口 貴久
SUZUKI, Yuichi
鈴木 裕一
ITO, Koichi
伊藤 康一
NIIJIMA, Jun
新島 淳
MIYAZAWA, Mamoru
宮澤 守
SHIMIZU, Toshikazu
清水 寿一
GOTODA, Masaharu
後藤田 正晴
SUZUKI, Naoko
鈴木 直子
HASEBE, Takashi
長谷部 隆
Inventors: SAKAGUCHI, Takahisa
坂口 貴久
SUZUKI, Yuichi
鈴木 裕一
ITO, Koichi
伊藤 康一
NIIJIMA, Jun
新島 淳
MIYAZAWA, Mamoru
宮澤 守
SHIMIZU, Toshikazu
清水 寿一
GOTODA, Masaharu
後藤田 正晴
SUZUKI, Naoko
鈴木 直子
HASEBE, Takashi
長谷部 隆
Title: CRYSTAL OF INDOLE DERIVATIVE HAVING PIPERIDINE RING AND PROCESS FOR PRODUCTION THEREOF
Abstract:
A crystal of 1-[1-[2-(7-methoxy-2,2-dimethyl-4-oxochroman-8-yl)- ethyl]piperidin-4-yl]-N-methyl-1H-indole-6-carboxamide fumarate which has peaks at chemical shifts of about 124.0 ppm and about 26.8 ppm in a 13C solid NMR spectrum.