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Machine translation
1. (WO2006119071) METHODS AND USES OF LEUKOTRIENE B4 HYDROXYLASES TO TREAT DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/119071    International Application No.:    PCT/US2006/016357
Publication Date: 09.11.2006 International Filing Date: 01.05.2006
IPC:
G01N 33/53 (2006.01)
Applicants: CYTOMETIX, INC. [US/US]; 756 North Milwaukee Street, Suite 250, Milwaukee, Wisconsin 53202 (US) (For All Designated States Except US).
THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. [US/US]; 9200 West Wisconsin Avenue, Milwaukee, Wisconsin 53226 (US) (For All Designated States Except US).
HARDER, David, R. [US/US]; (US) (For US Only).
ANTCZAK, James, B. [US/US]; (US) (For US Only).
BROSTROM, Lane [US/US]; (US) (For US Only)
Inventors: HARDER, David, R.; (US).
ANTCZAK, James, B.; (US).
BROSTROM, Lane; (US)
Agent: LEECK, Charles; QUARLES & BRADY LLP, 411 E. Wisconsin Avenue, Milwaukee, WI 53202 (US)
Priority Data:
60/676,369 29.04.2005 US
Title (EN) METHODS AND USES OF LEUKOTRIENE B4 HYDROXYLASES TO TREAT DISEASES
(FR) PROCEDES ET UTILISATIONS D'HYDROXYLASES DE LEUKOTRIENE B4 DESTINES A TRAITER DES MALADIES
Abstract: front page image
(EN)Methods and uses are described for treating or preventing diseases of humans or non-human animals by reducing the amount of active leukotriene B4 (LTB4) in those in need of such treatment using LTB4 hydroxylases. In certain embodiments, LTB4 hydroxylase is administered in combination with nicotinamide adenine dinucleotide phosphate and/or an NADPH-cytochrome P-450 reductase. The invention is particularly useful for treating or preventing respiratory diseases that are caused or exacerbated by inflammation.
(FR)L'invention concerne des procédés et des utilisations destinés à traiter ou à prévenir des maladies d'animaux humains ou non humains par réduction de la quantité de leukotriène B4 (LTB4) chez des animaux nécessitant un tel traitement au moyen d'hydroxylases LTB4. Dans certains modes de réalisation, l'hydroxylase LTB4 est administré en combinaison avec du phosphate dinucléotide d'adénine nicotinamide et/ou de la réductase P-450 de NADPH-cytochrome P-450. L'invention est particulièrement utile dans le traitement ou la prévention de maladies respiratoires causées ou provoquées par une inflammation.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)