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1. (WO2006117609) PHENOXYPROPYLPIPERIDINES AND -PYRROLIDINES AND THEIR USE AS HISTAMINE H3 -RECEPTOR LIGANDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/117609    International Application No.:    PCT/IB2006/000991
Publication Date: 09.11.2006 International Filing Date: 25.04.2006
IPC:
C07D 295/088 (2006.01), C07D 213/30 (2006.01), C07D 211/68 (2006.01), C07D 333/16 (2006.01), C07D 211/14 (2006.01), C07D 401/10 (2006.01), A61K 31/40 (2006.01), A61K 31/44 (2006.01), A61K 31/381 (2006.01), A61K 31/5377 (2006.01), A61P 25/00 (2006.01)
Applicants: BIOPROJET [FR/FR]; 30, rue des Francs-Bourgeois, F-75003 Paris (FR) (For All Designated States Except US).
BERTRAND, Isabelle [FR/FR]; (FR) (For US Only).
CAPET, Marc [FR/FR]; (FR) (For US Only).
LECOMTE, Jeanne-Marie [FR/FR]; (FR) (For US Only).
LEVOIN, Nicolas [FR/FR]; (FR) (For US Only).
LIGNEAU, Xavier [FR/FR]; (FR) (For US Only).
POUPARDIN-OLIVIER, Olivia [FR/FR]; (FR) (For US Only).
ROBERT, Philippe [FR/FR]; (FR) (For US Only).
SCHWARTZ, Jean-Charles [FR/FR]; (FR) (For US Only).
LABEEUW, Olivier [FR/FR]; (FR) (For US Only)
Inventors: BERTRAND, Isabelle; (FR).
CAPET, Marc; (FR).
LECOMTE, Jeanne-Marie; (FR).
LEVOIN, Nicolas; (FR).
LIGNEAU, Xavier; (FR).
POUPARDIN-OLIVIER, Olivia; (FR).
ROBERT, Philippe; (FR).
SCHWARTZ, Jean-Charles; (FR).
LABEEUW, Olivier; (FR)
Agent: COLOMBET, Alain; Cabinet LAVOIX, 2, Place d'Estienne d'Orves, F-75441 Paris Cedex 09 (FR)
Priority Data:
05290950.4 29.04.2005 EP
60/678,243 06.05.2005 US
05291793.7 26.08.2005 EP
Title (EN) PHENOXYPROPYLPIPERIDINES AND -PYRROLIDINES AND THEIR USE AS HISTAMINE H3 -RECEPTOR LIGANDS
(FR) NOUVEAUX LIGANDS DU RECEPTEUR H3 DE L'HISTAMINE ET LEURS APPLICATIONS THERAPEUTIQUES
Abstract: front page image
(EN)The present patent application concerns compounds of formula (I) with R1 and R2 taken together with the nitrogen atom to which they are attached, form a mono or bicyclic saturated nitrogen-containing ring; their preparation and their use as a H3 receptor ligand for treating e.g. CNS disorders like Alzheimer's disease.
(FR)La présente invention se rapporte à de nouveaux composés représentés par la formule (I), à leur procédé de préparation et à leur utilisation thérapeutique.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)