WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2006117370) 4-PHENYL-5-OXO-l,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/117370    International Application No.:    PCT/EP2006/061976
Publication Date: 09.11.2006 International Filing Date: 02.05.2006
IPC:
A61K 31/47 (2006.01), C07D 215/20 (2006.01), C07D 401/12 (2006.01), C07D 405/12 (2006.01), C07D 417/12 (2006.01), A61K 31/4709 (2006.01), A61P 5/24 (2006.01)
Applicants: N.V. ORGANON [NL/NL]; Kloosterstraat 6, NL-5349 AB Oss (NL) (For All Designated States Except US).
TIMMERS, Cornelis, Marius [NL/NL]; (NL) (For US Only).
KARSTENS, Willem, Frederik, Johan [NL/NL]; (NL) (For US Only).
GRIMA POVEDA, Pedro, Manuel [ES/NL]; (NL) (For US Only)
Inventors: TIMMERS, Cornelis, Marius; (NL).
KARSTENS, Willem, Frederik, Johan; (NL).
GRIMA POVEDA, Pedro, Manuel; (NL)
Agent: KRAAK, Hajo; N.V. Organon, Global Patent Department, P.O. Box 20, NL-5340 BH Oss (NL)
Priority Data:
05103738.0 04.05.2005 EP
Title (EN) 4-PHENYL-5-OXO-l,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES AS MEDICAMENTS FOR THE TREATMENT OF INFERTILITY
(FR) DERIVES DE 4-PHENYL-5-OXO-1,4,5,6,7,8-HEXAHYDROQUINOLINE SERVANT DE MEDICAMENTS POUR TRAITER L'INFERTILITE
Abstract: front page image
(EN)The invention relates to a 4-phenyl-5-oxo-l,4,5,6,7,8-hexahydroquinoline derivative according to Formula (I), wherein the substituents are defined as in the description, or a pharmaceutically salt thereof. The compounds of this invention are potent FSH receptor activators and may be used for treating fertility disorders in e.g. controlled ovarian hyperstimulation and IVF procedures.
(FR)L'invention concerne un dérivé de 4-phényl-5-oxo-1,4,5,6,7,8-hexahydroquinoline de formule (I). Dans cette formule, les substituants sont définis dans la description. L'invention concerne également un sel pharmaceutiquement acceptable de ces dérivés. Les composés de l'invention sont de puissants activateurs du récepteur de FSH et peuvent être utilisés pour traiter des troubles de fertilité dans des procédures IVF et dans des procédures d'hyperstimulation ovarienne contrôlée.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)