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Machine translation
1. (WO2006117166) MRI CONTRAST AGENTS ENDOWED WITH CONCENTRATION INDEPENDENT RESPONSIVENESS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/117166    International Application No.:    PCT/EP2006/004023
Publication Date: 09.11.2006 International Filing Date: 28.04.2006
IPC:
A61K 49/14 (2006.01), A61K 49/10 (2006.01)
Applicants: BRACCO IMAGING SPA [IT/IT]; Via Egidio Folli 50, I-20134 Milano (IT) (For All Designated States Except US).
AIME, Silvio [IT/IT]; (IT) (For US Only).
TERRENO, Enzo [IT/IT]; (IT) (For US Only)
Inventors: AIME, Silvio; (IT).
TERRENO, Enzo; (IT)
Agent: POLETTI, Marco; Bracco Imaging SpA, Via Egidio Folli, 50, I-20134 Milano (IT)
Priority Data:
05103567.3 29.04.2005 EP
Title (EN) MRI CONTRAST AGENTS ENDOWED WITH CONCENTRATION INDEPENDENT RESPONSIVENESS
(FR) AGENTS DE CONTRASTE IRM DOTES D'UNE REACTIVITE INDEPENDANTE DE LA CONCENTRATION
Abstract: front page image
(EN)The present invention relates to a method for the in vivo, ex vivo, or in vitro determination of physical or chemical parameters of diagnostic interest by use of a slow tumbling paramagnetic agent that is responsive to changes of said physical or chemical parameter through changes in the R2p/R1p ratio allowing the determination of the said parameter in a manner that is independent on the actual agent concentration.
(FR)L'invention concerne un procédé permettant de déterminer in vivo, ex vivo, ou in vitro des paramètres physiques ou chimiques d'intérêt diagnostique par utilisation d'un agent paramagnétique à mobilité ralentie qui réagit à des changements dudit paramètre physique ou chimique par le biais de changements au niveau du rapport R2p/R1p, ce qui permet de déterminer ledit paramètre d'une manière indépendante de la concentration d'agent réelle.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)