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Machine translation
1. (WO2006116699) METHOD AND SYSTEM FOR ABSOLUTE PLATELET PERCENT AGGREGATION DETERMINATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/116699    International Application No.:    PCT/US2006/016289
Publication Date: 02.11.2006 International Filing Date: 26.04.2006
IPC:
C12Q 1/56 (2006.01), G01N 33/00 (2006.01), G01N 33/48 (2006.01), G01N 33/86 (2006.01)
Applicants: ACCUMETRICS, INC. [US/US]; 3985 Sorrento Valley Blvd., San Diego, California 92121 (US) (For All Designated States Except US).
SWAIM, Lisa [US/US]; (US) (For US Only).
DURBIN, Dennis [US/US]; (US) (For US Only)
Inventors: SWAIM, Lisa; (US).
DURBIN, Dennis; (US)
Agent: DAVIS, Paul; HELLER EHRMAN LLP, 275 Middlefield Road, Menlo Park, California 94025 (US)
Priority Data:
60/675,513 27.04.2005 US
11/411,239 24.04.2006 US
Title (EN) METHOD AND SYSTEM FOR ABSOLUTE PLATELET PERCENT AGGREGATION DETERMINATION
(FR) PROCEDE ET SYSTEME DE DETERMINATION ABSOLUE DU POURCENTAGE D'AGREGATION PLAQUETTAIRE
Abstract: front page image
(EN)A method for obtaining a percent aggregation or inhibition of platelets resulting from anti-platelet using a single blood sample is achieved . An assay device is provided. The assay device has multiple channels, each coupled to a common introduction port. A first platelet activator is sensitive to activation pathway targeted by the anti-platelet drug. A second platelet activator is insensitive to the activation pathway targeted by the anti-platelet drug. An anti-coagulated sample is introduced simultaneously to the first and second channels. A level of platelet aggregation is simultaneously made in both channels.
(FR)L'invention concerne un procédé permettant d'obtenir un pourcentage d'agrégation ou d'inhibition plaquettaire provenant d'une antiplaquette au moyen d'un unique échantillon sanguin. L'invention concerne également un dispositif d'analyse comprenant de multiples canaux, chacun d'eux étant couplé à un orifice d'introduction commun. Un premier activateur de plaquette est sensible au parcours d'activation ciblé par le médicament antiplaquettaire. Un second activateur de plaquette est insensible au parcours d'activation ciblé par le médicament antiplaqettaire. Un échantillon anti-coagulé est introduit simultanément dans le premier et le second canaux. Un niveau d'agrégation de plaquettes est simultanément obtenu dans les deux canaux.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)