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1. (WO2006116637) RAMAN SPECTROSCOPY FOR NON-INVASIVE GLUCOSE MEASUREMENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/116637    International Application No.:    PCT/US2006/016107
Publication Date: 02.11.2006 International Filing Date: 27.04.2006
IPC:
G01N 21/65 (2006.01)
Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY [US/US]; 77 Massachusetts Avenue, Cambridge, Massachusetts 02139-4307 (US) (For All Designated States Except US).
HUNTER, Martin [US/US]; (US) (For US Only).
ENEJDER, Annika, M. [SE/SE]; (SE) (For US Only).
SCECINA, Thomas [US/US]; (US) (For US Only).
FELD, Michael, S. [US/US]; (US) (For US Only).
SHIH, Wei-Chuan [--/US]; (US) (For US Only)
Inventors: HUNTER, Martin; (US).
ENEJDER, Annika, M.; (SE).
SCECINA, Thomas; (US).
FELD, Michael, S.; (US).
SHIH, Wei-Chuan; (US)
Agent: HOOVER, Thomas, O.; WEINGARTEN, SCHURGIN, GAGNEBIN & LEBOVICI, LLP, Ten Post Office Square, Boston, Massachusetts 02109 (US)
Priority Data:
60/675,252 27.04.2005 US
Title (EN) RAMAN SPECTROSCOPY FOR NON-INVASIVE GLUCOSE MEASUREMENTS
(FR) SPECTROSCOPIE RAMAN POUR DES MESURES DE GLUCOSE NON INVASIVES
Abstract: front page image
(EN)The present invention relates to the use of Raman spectroscopy for quantitative, non-invasive transcutaneous measurement of blood analytes, such as glucose. Raman spectroscopy is used to measure glucose trans cutaneously, in patients whose blood glucose levels were monitored. Raman spectra were collected trans cutaneously along with glucose reference values provided by standard capillary blood analysis. A partial least squares calibration was created from the data from each subject and validated using leave-one-out cross validation.
(FR)La présente invention concerne l'utilisation de la spectroscopie Raman pour une mesure quantitative, non invasive et transcutanée d'analytes sanguins, tels que le glucose. La spectroscopie Raman est utilisée pour mesurer le glucose par voie transcutanée chez des patients dont la glycémie est surveillée. Des spectres Raman sont collectés par voie transcutanée avec des valeurs de référence de glucose fournies par une analyse de sang capillaire standard. Un étalonnage partiel par les moindres carrés est établi à partir des données provenant de chaque sujet, puis validé en utilisant une validation croisée « leave-one-out ».
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)