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1. (WO2006116514) MICRONIZED TANAPROGET, COMPOSITIONS, AND METHODS OF PREPARING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/116514    International Application No.:    PCT/US2006/015837
Publication Date: 02.11.2006 International Filing Date: 26.04.2006
IPC:
A61K 31/536 (2006.01), A61K 9/16 (2006.01), A61K 9/20 (2006.01), A61K 9/28 (2006.01)
Applicants: WYETH [US/US]; Five Giralda Farms Madison, New Jersey 07940 (US) (For All Designated States Except US).
NAGI, Arwinder [US/US]; (US) (For US Only).
CHATLAPALLI, Ramarao [US/US]; (US) (For US Only).
HASAN, Shamim [US/US]; (US) (For US Only).
GHORAB, Mohamed [EG/US]; (US) (For US Only).
GAGLANI, Dhaval [IN/US]; (US) (For US Only)
Inventors: NAGI, Arwinder; (US).
CHATLAPALLI, Ramarao; (US).
HASAN, Shamim; (US).
GHORAB, Mohamed; (US).
GAGLANI, Dhaval; (US)
Agent: KODROFF, Cathy, A.; Howson and Howson, 501 Office Center Drive, Suite 210, Fort Washington, PA 19034 (US)
Priority Data:
60/675,550 28.04.2005 US
Title (EN) MICRONIZED TANAPROGET, COMPOSITIONS, AND METHODS OF PREPARING THE SAME
(FR) TANAPROGET MICRONISE, COMPOSITIONS ET PROCEDE POUR LES PREPARER
Abstract: front page image
(EN)The present invention provides compositions, desirably pharmaceutical compositions, containing micronized tanaproget. The compositions can also contain microcrystalline cellulose, croscarmellose sodium, anhydrous lactose, magnesium stearate, micronized edetate calcium disodium hydrous, and micronized sodium thiosulfate pentahydrate. The compositions are useful in contraception and hormone replacement therapy and in the treatment and/or prevention of uterine myometrial fibroids, benign prostatic hypertrophy, benign and malignant neoplastic disease, dysfunctional bleeding, uterine leiomyomata, endometriosis, polycystic ovary syndrome, and carcinomas and adenocarcinomas of the pituitary, endometrium, kidney, ovary, breast, colon, and prostate and other hormone-dependent tumors, and in the preparation of medicaments useful therefor. Additional uses include stimulation of food intake.
(FR)La présente invention concerne des compositions, des compositions de préférence pharmaceutiques contenant du tanaproget micronisé. Les compositions peuvent également contenir du cellulose microcristallin, du sodium de croscarmellose, du lactose anhydre, du stéarate de magnésium, du sel disodique d'édétate de calcium hydraté micronisé, et du pentahydrate de thiosulfate de sodium micronisé. Les compositions sont utiles dans le cadre de la contraception et de la thérapie de remplacement hormonal, et dans le cadre du traitement et/ou de la prévention de fibroïdes du myomètre utérin, l'hypertrophie prostatique bénigne, la maladie néoplasique bénigne ou maligne, les saignements anormaux, le leiomyomata utérin, l'endométriose, le syndrome ovarien polycystique et des carcinomes et adénocarcinomes de l'hypophyse, de l'endomètre, du rein, de l'ovaire, du sein, du côlon et de la prostate, et d'autres tumeurs hormono-dépendantes, et dans le cadre de la préparation de médicaments utiles à cet effet. D'autres utilisations comprennent la stimulation de l'absorption d'aliments.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)