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1. (WO2006116353) N-ACETYLCYSTEINE AMIDE (NAC AMIDE) FOR THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED WITH OXIDATIVE STRESS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/116353    International Application No.:    PCT/US2006/015548
Publication Date: 02.11.2006 International Filing Date: 21.04.2006
IPC:
A61K 31/165 (2006.01), C07C 321/00 (2006.01)
Applicants: GOLDSTEIN, Glenn, A. [US/US]; (US)
Inventors: GOLDSTEIN, Glenn, A.; (US)
Agent: BISWAS, Naomi; MINTZ, LEVIN, COHN, FERRIS, GLOVSKY AND POPEO PC, One Financial Center, Boston, Massachusetts 02111 (US)
Priority Data:
60/673,561 21.04.2005 US
60/705,967 05.08.2005 US
Title (EN) N-ACETYLCYSTEINE AMIDE (NAC AMIDE) FOR THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED WITH OXIDATIVE STRESS
(FR) AMIDE N-ACETYLCYSTEINE (AMIDE NAC) DESTINE AU TRAITEMENT DE MALADIES ET DE TROUBLES ASSOCIES AU STRESS OXYDATIF
Abstract: front page image
(EN)Methods and compositions comprising N-acetylcysteine amide (NAC amide) and derivatives thereof are used in treatments and therapies for human and non-human mammalian diseases, disorders, conditions and pathologies. Pharmaceutically or physiologically acceptable compositions of NAC amide or derivatives thereof are administered alone, or in combination with other suitable agents, to reduce, prevent, or counteract oxidative stress and free radical oxidant formation and overproduction in cells and tissues, as well as to provide a new source of glutathione.
(FR)L'invention concerne des procédés et des compositions contenant un amide N-acetylcystéine (amide NAC) et des dérivés de celui-ci utilisés dans des traitements et des thérapies contre des maladies, des troubles, des conditions et des pathologies de mammifères humains et non-humains. Les compositions acceptables sur le plan pharmaceutique et physiologique d'amide NAC ou des dérivés de ceux-ci sont administrés seuls, ou en combinaison avec d'autres agents appropriés, afin de réduire, prévenir ou annihiler la formation du stress oxydatif et d'agent oxydant à radicaux libres et sa surproduction dans des cellules et des tissus, ainsi que pour produire une nouvelle source de glutathione.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)