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1. (WO2006116001) ANTIBODIES FOR THE TREATMENT OF CANCERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/116001    International Application No.:    PCT/US2006/014941
Publication Date: 02.11.2006 International Filing Date: 20.04.2006
IPC:
A61K 39/00 (2006.01), A61K 39/395 (2006.01), C07K 16/00 (2006.01), C12P 21/08 (2006.01)
Applicants: WELSON PHARMACEUTICALS, INC. [CN/CN]; R & D Plaza B1115, Tshinghua University, Beijing 100084 (CN) (For All Designated States Except US).
SUN, Le [US/US]; (US) (For US Only)
Inventors: SUN, Le; (US)
Agent: VAN DYKE, Raymond; Winston & Strawn, LLP, Patent Department, 1700 K Street, N.W., Washington, DC 20006 (US)
Priority Data:
60/675,094 27.04.2005 US
Title (EN) ANTIBODIES FOR THE TREATMENT OF CANCERS
(FR) ANTICORPS POUR LE TRAITEMENT DE CANCERS
Abstract: front page image
(EN)The present invention features monoclonal antibodies LA1 or LA22 conjugated with mitomycin C, pingyangmycin or other anti-cellular agents. The present invention also features other anti-EGFR antibodies conjugated with mitomycin C or pingyangmycin. The antibodies of the present invention can be used to treat cancers, including but not limited to, those of epithelial origin, such as glioblastoma or cancer of the lung, breast, head and neck, and bladder.
(FR)L'invention concerne des anticorps monoclonaux LA1 ou LA22 conjugués avec la mitomycine C, la pingyangmycine ou d'autres agents anti-cellulaires. L'invention concerne également d'autres anticorps anti-EGFR conjugués avec la mitomycine C ou la pingyangmycine. Les anticorps selon l'invention peuvent être utilisés pour traiter des cancers, notamment ceux d'origine épithéliale, par exemple le glioblastome ou le cancer des poumons, du sein, de la tête et du cou, ainsi que de la vessie.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)