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1. (WO2006114765) MRI INVOLVING CONTRAST AGENT WITH TIME MODULATED CONTRAST ENHANCEMENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/114765    International Application No.:    PCT/IB2006/051286
Publication Date: 02.11.2006 International Filing Date: 25.04.2006
IPC:
G01R 33/28 (2006.01)
Applicants: KONINKLIJKE PHILIPS ELECTRONICS N.V. [NL/NL]; Groenewoudseweg 1, NL-5621 BA Eindhoven (NL) (For All Designated States Except US).
WILLARD, Nicolaas, P. [NL/NL]; (NL) (For US Only).
WEGH, Rene, T. [NL/NL]; (NL) (For US Only).
PIKKEMAAT, Jeroen, A. [NL/NL]; (NL) (For US Only).
GRUELL, Holger [DE/NL]; (NL) (For US Only).
SCHAEFFTER, Tobias [DE/GB]; (NL) (For US Only).
LAMERICHS, Rudolf, M., J., N. [NL/NL]; (NL) (For US Only)
Inventors: WILLARD, Nicolaas, P.; (NL).
WEGH, Rene, T.; (NL).
PIKKEMAAT, Jeroen, A.; (NL).
GRUELL, Holger; (NL).
SCHAEFFTER, Tobias; (NL).
LAMERICHS, Rudolf, M., J., N.; (NL)
Agent: COHEN, Julius, S.; Prof. Holstlaan 6, NL-5656 AA Eindhoven (NL)
Priority Data:
05103351.2 26.04.2005 EP
Title (EN) MRI INVOLVING CONTRAST AGENT WITH TIME MODULATED CONTRAST ENHANCEMENT
(FR) PROCEDE ET DISPOSITIF PERMETTANT UNE DETECTION AMELIOREE DE LA DENSIFICATION EN IRM
Abstract: front page image
(EN)The present invention provides a method of MRI imaging. By applying a time modulation to the contrast enhancement of an MRI contrast agent such as a CEST contrast agent, the method according to the invention leads to images with improved signal-to-noise ratio in the contrast-enhanced areas, strongly suppressed unwanted signal in the unenhanced areas, and reduced artefacts, such as motion artefacts .
(FR)L'invention concerne un procédé d'imagerie IRM. Par l'application d'une modulation temporelle à la densification produite par un agent de contraste IRM, le procédé décrit permet d'obtenir des images présentant un rapport signal-bruit amélioré dans les zones de densification, un niveau élevé de suppression des signaux indésirables dans les zones non densifiées, et une réduction des artefacts tels que les artefacts dus aux mouvements.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)