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1. WO2006112685 - NEUROTHERAPEUTIC AZOLE COMPOUNDS

Publication Number WO/2006/112685
Publication Date 26.10.2006
International Application No. PCT/KR2006/001523
International Filing Date 21.04.2006
IPC
C07D 257/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
257Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
02not condensed with other rings
04Five-membered rings
CPC
A61K 31/4192
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
41921,2,3-Triazoles
A61P 21/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
21Drugs for disorders of the muscular or neuromuscular system
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 25/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
06Antimigraine agents
A61P 25/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
08Antiepileptics; Anticonvulsants
A61P 25/20
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
20Hypnotics; Sedatives
Applicants
  • SK HOLDINGS CO., LTD. [KR]/[KR] (AllExceptUS)
  • CHOI, Yong-Moon [US]/[US] (UsOnly)
  • KIM, Choon-Gil [KR]/[KR] (UsOnly)
  • KANG, Young-Sun [KR]/[KR] (UsOnly)
  • YI, Han-Ju [KR]/[KR] (UsOnly)
  • LEE, Hyun-Seok [KR]/[KR] (UsOnly)
  • KU, Bon-Chul [KR]/[KR] (UsOnly)
  • LEE, Eun-Ho [KR]/[KR] (UsOnly)
  • IM, Dae-Joong [KR]/[KR] (UsOnly)
  • SHIN, Yu-Jin [KR]/[KR] (UsOnly)
Inventors
  • CHOI, Yong-Moon
  • KIM, Choon-Gil
  • KANG, Young-Sun
  • YI, Han-Ju
  • LEE, Hyun-Seok
  • KU, Bon-Chul
  • LEE, Eun-Ho
  • IM, Dae-Joong
  • SHIN, Yu-Jin
Agents
  • C & S LOGOS PATENT AND LAW OFFICE
Priority Data
60/674,53022.04.2005US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) NEUROTHERAPEUTIC AZOLE COMPOUNDS
(FR) COMPOSES AZOLE NEUROTHERAPEUTIQUES
Abstract
(EN) Azole compounds containing carbamoyl group and pharmaceutically useful salts thereof are described. The compounds are effective anticonvulsants which are used in the treatment of disorders of the central nervous system, especially as anxiety, depression, convulsion, epilepsy, migraine, bipolar disorder, drug abuse, smoking, ADHD, obesity, sleep disorder, neuropathic pain, stroke, cognitive impairment, neurodegeneration, stroke and muscle spasm.
(FR) Composés azole contenant un groupe carbamoyle et sels pharmaceutiquement utiles correspondants, efficaces comme anticonvulsifs dans le traitement des troubles du système nerveux central, en particulier l'anxiété, la dépression, les convulsions, l'épilepsie, la migraine, les troubles bipolaires, l'abus de drogues, l'abus du tabac, le trouble d'hyperactivité avec déficit de l'attention, l'obésité, les troubles du sommeil, la douleur neuropathique, la déficience cognitive, la neurodégénérescence, l'accident vasculaire cérébral et les spasmes musculaires.
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