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1. (WO2006109190) TETRACYCLIC MONOAMINE REUPTAKE INHIBITORS FOR TREATMENT OF CNS DISEASES AND DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2006/109190 International Application No.: PCT/IB2006/001480
Publication Date: 19.10.2006 International Filing Date: 01.02.2006
IPC:
C07D 495/04 (2006.01) ,A61K 31/55 (2006.01) ,A61P 25/24 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
495
Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
55
having seven-membered rings, e.g. azelastine, pentylenetetrazole
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
24
Antidepressants
Applicants:
MESIC, Milan [HR/HR]; HR (UsOnly)
MERCEP, Mladen [HR/HR]; HR (UsOnly)
PESIC, Dijana [HR/HR]; HR (UsOnly)
RUPCIC, Renata [HR/HR]; HR (UsOnly)
STANIC, Barbara [HR/HR]; HR (UsOnly)
GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O. [HR/HR]; Prilaz Baruna Filipovica 29 10000 Zagrab, HR (AllExceptUS)
Inventors:
MESIC, Milan; HR
MERCEP, Mladen; HR
PESIC, Dijana; HR
RUPCIC, Renata; HR
STANIC, Barbara; HR
Priority Data:
60/649,80702.02.2005US
Title (EN) TETRACYCLIC MONOAMINE REUPTAKE INHIBITORS FOR TREATMENT OF CNS DISEASES AND DISORDERS
(FR) INHIBITEURS DE REABSORPTION DE MONOAMINES TETRACYCLIQUES POUR LE TRAITEMENT DE MALADIES ET TROUBLES DU SYSTEME NERVEUX CENTRAL
Abstract:
(EN) Novel tetracyclic dibenzo (e,h) azulene compounds of formula (I); their pharmacologically acceptable derivatives; pharmaceutical compositions containing them and their activity and use in the treatment of central nervous system (CNS) diseases and conditions in humans and animals.
(FR) La présente invention a trait à de nouveaux composés tétracycliques à base de dibenzo(e,h)azulène, représentés pas la formule (I), à leurs dérivés pharmacologiquement acceptables, à des compositions pharmaceutiques les contenant et à leur activité et utilisation dans le traitement de maladies et conditions du système nerveux central (CNS) chez les humains et les animaux.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)