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1. WO2006102308 - BETA-LACTAMYL VASOPRESSIN V1B ANTAGONISTS

Publication Number WO/2006/102308
Publication Date 28.09.2006
International Application No. PCT/US2006/010192
International Filing Date 21.03.2006
IPC
A61K 31/395 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
CPC
A61K 31/397
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
397having four-membered rings, e.g. azetidine
A61P 15/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
A61P 25/22
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
22Anxiolytics
A61P 25/24
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
24Antidepressants
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
A61P 5/24
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
5Drugs for disorders of the endocrine system
24of the sex hormones
Applicants
  • AZEVAN PHARMACEUTICALS, INC. [US]/[US] (AllExceptUS)
  • KOPPEL, Gary, A. [US]/[US] (UsOnly)
Inventors
  • KOPPEL, Gary, A.
Agents
  • ADDISON, Bradford, G.
Priority Data
60/664,23922.03.2005US
60/700,67319.07.2005US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BETA-LACTAMYL VASOPRESSIN V1B ANTAGONISTS
(FR) ANTAGONISTES DE BÊTA-LACTAMYL VASOPRESSINE V1B
Abstract
(EN)
Substituted 2-(azetidin-2-on-l-yl)alkanedioic acids, substituted 2- (azetidin-2-on-l-yl)hydroxyalkylalkanoic acids, and 2-(azetidin-2-on-l- yl)thiolalkylalkanoic acids, and analogs and derivatives thereof are described. Methods for using 2-(azetidin-2-on-l-yl)alkanedioic acids and derivatives thereof in the treatment of disease states responsive to antagonism of the vasopressin Vib receptor are also described.
(FR)
La présente invention concerne des acides 2-(azétidin-2-on-1-yl)alcanedioïques substitués, des acides 2-(azétidin-2-on-1-yl)hydroxyalkylalcanoïques substitués, et des acides 2-(azétidin-2-on-1-yl)thiolalkylalcanoïques, et des analogues et dévirés de ceux-ci. L'invention a également pour objet des procédés pour utiliser des acides 2-(azétidin-2-on-1-yl)alcanedioïques et leurs dérivés, dans le cadre du traitement d'états pathologiques répondant à l'antagonisme du récepteur de la vasopressine V1b.
Also published as
EP6748509
Latest bibliographic data on file with the International Bureau