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1. WO2006099958 - USE OF SUBSTITUTED 2-THIO-3,5-DICYANO-4-PHENYL-6-AMINOPYRIDINES FOR THE TREATMENT OF REPERFUSION INJURY AND REPERFUSION DAMAGE

Publication Number WO/2006/099958
Publication Date 28.09.2006
International Application No. PCT/EP2006/002263
International Filing Date 11.03.2006
IPC
A61K 31/44 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
A61P 9/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
10for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
CPC
A61K 31/44
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
A61P 9/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
A61P 9/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
10for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applicants
  • BAYER HEALTHCARE AG [DE]/[DE] (AllExceptUS)
  • KRAHN, Thomas [DE]/[DE] (UsOnly)
  • KRÄMER, Thomas [DE]/[DE] (UsOnly)
  • ROSENTRETER, Ulrich [DE]/[DE] (UsOnly)
  • DOWNEY, James, M. [US]/[US] (UsOnly)
  • SOLENKOVA, Natalia [US]/[US] (UsOnly)
Inventors
  • KRAHN, Thomas
  • KRÄMER, Thomas
  • ROSENTRETER, Ulrich
  • DOWNEY, James, M.
  • SOLENKOVA, Natalia
Common Representative
  • BAYER HEALTHCARE AG
Priority Data
60/665,63124.03.2005US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) USE OF SUBSTITUTED 2-THIO-3,5-DICYANO-4-PHENYL-6-AMINOPYRIDINES FOR THE TREATMENT OF REPERFUSION INJURY AND REPERFUSION DAMAGE
(FR) UTILISATION DE 2-THIO-3,5-DICYANO-4-PHENYL-6-AMINOPYRIDINES SUBSTITUEES POUR TRAITER LES LESIONS DE REPERFUSION ET LES DOMMAGES DE REPERFUSION
Abstract
(EN)
The invention relates to substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines of formula (I) and their use in medicaments for the prophylaxis and/or treatment of reperfusion injury and damage.
(FR)
La présente invention se rapporte à des 2-thio-3,5-dicyano-4-phényl-6-aminopyridines substituées, représentées par la formule (I), et à leur utilisation dans des médicaments destinés à prévenir et/ou à traiter les lésions et les dommages de reperfusion.
Latest bibliographic data on file with the International Bureau