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1. WO2006098464 - METHOD FOR DIAGNOSIS OF PROSTATE CANCER

Publication Number WO/2006/098464
Publication Date 21.09.2006
International Application No. PCT/JP2006/305480
International Filing Date 14.03.2006
IPC
G01N 33/574 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
C07K 16/18 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
G01N 27/62 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
62by investigating the ionisation of gases; by investigating electric discharges, e.g. emission of cathode
CPC
C07K 16/3069
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
30from tumour cells
3069Reproductive system, e.g. ovaria, uterus, testes, prostate
G01N 33/564
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
564for pre-existing immune complex or autoimmune disease ; , i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
G01N 33/57434
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
57407Specifically defined cancers
57434of prostate
Applicants
  • リンク・ジェノミクス株式会社 LINK GENOMICS, INC. [JP]/[JP] (AllExceptUS)
  • 国立大学法人大阪大学 OSAKA UNIVERSITY [JP]/[JP]
  • PCA Intermed株式会社 PCA INTERMED, INC [JP]/[JP] (AllExceptUS)
  • 辻川 和丈 TSUJIKAWA, KAZUTAKE [JP]/[JP] (UsOnly)
  • 山元 弘 YAMAMOTO, Hiroshi [JP]/[JP] (UsOnly)
  • 小西 登 KONISHI, Noboru [JP]/[JP] (UsOnly)
Inventors
  • 辻川 和丈 TSUJIKAWA, KAZUTAKE
  • 山元 弘 YAMAMOTO, Hiroshi
  • 小西 登 KONISHI, Noboru
Agents
  • 小林 浩 KOBAYASHI, Hiroshi
Priority Data
2005-07138714.03.2005JP
2005-24141423.08.2005JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) METHOD FOR DIAGNOSIS OF PROSTATE CANCER
(FR) MÉTHODE POUR DIAGNOSTIQUER LE CANCER DE LA PROSTATE
(JA) 前立腺がんの診断方法
Abstract
(EN)
Disclosed is a method for the detection and/or quantification of PCA-1 in a body fluid sample from a subject as a marker of prostate cancer. Also disclosed is a method for the detection and/or quantification of an anti-PCA-1 autoantibody in a body fluid sample from a subject as a marker of prostate cancer. These methods enable to diagnose prostate cancer more rapidly in a simpler manner at lower cost.
(FR)
L’invention révèle une méthode pour la quantification et/ou la détection de PCA-1 dans un échantillon de liquide biologique d'un sujet comme marqueur du cancer de la prostate. Elle révèle aussi une méthode pour la quantification et/ou la détection d’un auto-anticorps anti-PCA-1 dans un échantillon de liquide biologique d'un sujet comme marqueur du cancer de la prostate. Ces méthodes permettent de diagnostiquer le cancer de la prostate plus rapidement, d’une manière plus simple et moins coûteuse.
(JA)
本発明は、被験者の体液試料中のPCA−1を前立腺がんマーカーとして検出および/または定量する方法を提供する。本発明はまた、被験者の体液試料中の抗PCA−1自己抗体を前立腺がんマーカーとして検出および/または定量する方法を提供する。本発明は、前立腺がんの診断をより簡易、迅速、安価にする。
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