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1. WO2006098006 - ANTI-INFLAMMATORY AGENT

Publication Number WO/2006/098006
Publication Date 21.09.2006
International Application No. PCT/JP2005/004562
International Filing Date 15.03.2005
IPC
A61K 35/78
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
78Materials from plants
A61K 7/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
7Cosmetics or similar toilet preparations
A61K 31/122
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
12Ketones
122having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
A61K 31/352
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61P 7/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
7Drugs for disorders of the blood or the extracellular fluid
02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
A61P 17/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
CPC
A61K 31/122
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
12Ketones
122having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
A61K 36/484
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
484Glycyrrhiza (licorice)
A61P 17/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
A61P 7/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
7Drugs for disorders of the blood or the extracellular fluid
02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Applicants
  • 丸善製薬株式会社 MARUZEN PHARMACEUTICALS CO., LTD. [JP]/[JP] (AllExceptUS)
  • 三宅 康夫 MIYAKE, Yasuo [JP]/[JP] (UsOnly)
  • 伊藤 洋子 ITO, Yoko [JP]/[JP] (UsOnly)
Inventors
  • 三宅 康夫 MIYAKE, Yasuo
  • 伊藤 洋子 ITO, Yoko
Agents
  • 廣田 浩一 HIROTA, Koichi
Priority Data
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) ANTI-INFLAMMATORY AGENT
(FR) AGENT ANTI-INFLAMMATOIRE
(JA) 抗炎症剤
Abstract
(EN)
An anti-inflammatory agent which comprises an oil-soluble licorice extract obtained by extraction treatment of at least either a leguminous plant of the genus Glycyrrhiza or a water extraction residue of a leguminous plant of the genus Glycyrrhiza with an organic solvent, and has at least one effect selected from an inhibitory effect on hyaluronidase activity, an inhibitory effect on hexosaminidase release (i.e., an inhibitory effect on histamine release), an inhibitory effect on platelet aggregation and an inhibitory effect on phospholipase A2 activity.
(FR)
L’invention concerne un agent anti-inflammatoire qui comprend un extrait de réglisse soluble dans l’huile obtenu par traitement d'extraction au moins à partir soit d'une plante légumineuse du genre Glycyrrhiza soit d’un résidu d'extraction à l'eau d'une plante légumineuse du genre Glycyrrhiza avec un solvant organique, et qui a au moins un effet sélectionné parmi un effet inhibiteur de l’activité de l'hyaluronidase, un effet inhibiteur de la libération d’hexosaminidase (c.-à-d., un effet inhibiteur de la libération d'histamine), un effet inhibiteur de l’agrégation plaquettaire et un effet inhibiteur de l’activité de la phospholipase A2.
(JA)
 本発明は、マメ科グリチリザ(Glycyrrhiza)属植物、及びマメ科グリチリザ(Glycyrrhiza)属植物の水抽出残渣の少なくともいずれかを有機溶媒で抽出処理して得られる油溶性甘草抽出物を含有してなり、ヒアルロニダーゼ活性阻害作用、ヘキソサミニダーゼ遊離抑制作用(即ち、ヒスタミン遊離抑制作用)、血小板凝集抑制作用及びホスホリパーゼA活性阻害作用から選択される少なくとも1種の作用を有する抗炎症剤である。
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