Processing

Please wait...

Settings

Settings

Goto Application

1. WO2006097707 - SKIN COMPOSITION TREATMENT

Considered void:  10.11.2006
Publication Number WO/2006/097707
Publication Date 21.09.2006
International Application No. PCT/GB2006/000900
International Filing Date 14.03.2006
IPC
C12N 5/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
C12N 13/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
13Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
A61P 17/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
02for treating wounds, ulcers, burns, scars, keloids, or the like
CPC
A61K 35/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
A61K 41/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
41Medicinal preparations obtained by treating materials with wave energy or particle radiation ; ; Therapies using these preparations
A61P 17/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
02for treating wounds, ulcers, burns, scars, keloids, or the like
C12N 13/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
13Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
C12N 2533/56
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2533Supports or coatings for cell culture, characterised by material
50Proteins
56Fibrin; Thrombin
C12N 5/0062
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor;
0062General methods for three-dimensional culture
Applicants
  • INTERCYTEX LIMITED [GB]/[GB] (AllExceptUS)
  • JOHNSON, Penny [CA]/[GB] (UsOnly)
  • MARSHALL, Damian [GB]/[GB] (UsOnly)
  • MARKX, Gerard [GB]/[GB] (UsOnly)
Inventors
  • JOHNSON, Penny
  • MARSHALL, Damian
  • MARKX, Gerard
Agents
  • DAVIES, Jonathan, Mark
Priority Data
0505203.014.03.2005GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SKIN COMPOSITION TREATMENT
(FR) TRAITEMENT DE COMPOSITIONS DE PEAU
Abstract
(EN)
Compositions such as skin equivalents and methods for their manufacture. In particular, a method for modulating the tensile strength and/or elastic strength of a composition comprising living cells suspended in a 3-D support matrix, which method includes the step of subjecting the composition to ultrasound stimulation, characterised in that the ultrasound stimulation comprises alternating periods of exposure to ultrasound followed by rest periods, in a continuous cycle over a period of at least 21 days in which the duration of each period of exposure is about 1 s to 10 min, for example about 5 min or 2 min, preferably about 10 s, and in which the duration of each rest period is about 1 s to 30 min, for example about 15 min or 10 min, preferably 180 s, and in which the ultrasound stimulation has a pulse frequency of about 250 kHz to 50 MHz, for example about 500 kHz to 20 MHz, preferably 1 MHz.
(FR)
Compositions tels que des équivalents de peau et procédés de production desdites compositions. La présente invention concerne en particulier un procédé permettant de moduler la résistance à la traction et / ou la résistance élastique d'une composition contenant des cellules vivantes en suspension dans une matrice de support en trois dimensions. Ledit procédé consiste à soumettre la composition à la stimulation par ultrasons, ladite stimulation par ultrasons comportant en alternance des périodes d'exposition aux ultrasons et des périodes de repos, lors d'un cycle continu sur une période d'au moins 21 jours lors de laquelle la durée de chaque période d'exposition est d'environ 1 s à 10 min, par exemple d'environ 5 min ou 2 min, de préférence d'environ 10 s, et lors de laquelle la durée de chaque période de repos est d'environ 1 s à 30 min, par exemple d'environ 15 min ou 10 min, de préférence 180 s. La stimulation par ultrasons possède une fréquence d'impulsions d'environ 250 kHz à 50 MHz, par exemple d'environ 500 kHz à 20 MHz, et de préférence de 1 MHz.
Latest bibliographic data on file with the International Bureau