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1. WO2006097342 - PROCESS FOR MAKING STEROIDAL COMPOUNDS

Publication Number WO/2006/097342
Publication Date 21.09.2006
International Application No. PCT/EP2006/002584
International Filing Date 16.03.2006
IPC
C07J 41/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
41Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
CPC
C07J 21/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
21Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
C07J 41/0033
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
41Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
0033not covered by C07J41/0005
C07J 41/0094
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
JSTEROIDS
41Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
0033not covered by C07J41/0005
0094containing nitrile radicals, including thiocyanide radicals
Applicants
  • SYNTHON B.V. [NL]/[NL] (AllExceptUS)
  • GIELING, Reinerus, Gerardus [NL]/[NL] (UsOnly)
  • GROEN, Marinus, Bernard [NL]/[NL] (UsOnly)
Inventors
  • GIELING, Reinerus, Gerardus
  • GROEN, Marinus, Bernard
Agents
  • PRINS, Hendrik, Willem
Priority Data
60/662,54817.03.2005US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PROCESS FOR MAKING STEROIDAL COMPOUNDS
(FR) PROCEDE DE PREPARATION DE COMPOSES STEROIDES
Abstract
(EN)
The invention relates to a process, for forming an amide of formula (3), wherein the dotted line represents a single bond, a double bond, or an epoxy-bond which comprises reacting a nitrile of formula (2), wherein the dotted line has the same meaning as in formula (3) with water in the presence of a noble metal catalyst, especially a platinum complex of dialkyl- or diaryl-phosphine oxides.
(FR)
L'invention concerne un procédé de préparation d'un amide représenté par la formule (3), dans laquelle la ligne pointillée représente une liaison simple, une liaison double, ou une liaison époxyde. Ce procédé consiste à faire réagir un nitrile représenté par la formule (2), dans laquelle la ligne pointillée est identique à celle de la formule (3) dans l'eau en présence d'un catalyseur de métal noble, particulièrement, un complexe de platine d'oxydes de dialkyl- ou de diaryl-phosphine.
Also published as
EP6723591
Latest bibliographic data on file with the International Bureau