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1. WO2006097176 - PHTHALAZINONES

Publication Number WO/2006/097176
Publication Date 21.09.2006
International Application No. PCT/EP2006/001525
International Filing Date 21.02.2006
IPC
C07D 237/32 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
237Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
26condensed with carbocyclic rings or ring systems
30Phthalazines
32with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
C07D 409/12 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
409Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
A61K 31/502 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
50Pyridazines; Hydrogenated pyridazines
502ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61P 19/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
02for joint disorders, e.g. arthritis, arthrosis
A61P 25/28
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
28for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 35/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applicants
  • MERCK PATENT GMBH [DE]/[DE] (AllExceptUS)
  • BUCHSTALLER, Hans-Peter [DE]/[DE] (UsOnly)
  • FINSINGER, Dirk [DE]/[DE] (UsOnly)
  • SCHIEMANN, Kai [DE]/[DE] (UsOnly)
  • EMDE, Ulrich [DE]/[DE] (UsOnly)
  • ZENKE, Frank [DE]/[DE] (UsOnly)
  • AMENDT, Christiane [DE]/[DE] (UsOnly)
Inventors
  • BUCHSTALLER, Hans-Peter
  • FINSINGER, Dirk
  • SCHIEMANN, Kai
  • EMDE, Ulrich
  • ZENKE, Frank
  • AMENDT, Christiane
Common Representative
  • MERCK PATENT GMBH
Priority Data
10 2005 011 822.415.03.2005DE
Publication Language German (DE)
Filing Language German (DE)
Designated States
Title
(DE) PHTHALAZINONE
(EN) PHTHALAZINONES
(FR) PHTALAZINONES
Abstract
(DE)
Verbindungen der Formel I worin R, R1, R2, R3, R4, R5, R6, R7, R8, Z1, Z2, Z3 und Y1 die in Anspruch 1 angegebenen Bedeutungen haben, können u.a. zur Behandlung von Tumoren eingesetzt werden.
(EN)
The invention relates to compounds of formula I, wherein R, R1, R2, R3, R4, R5, R6, R7, R8, Z1, Z2, Z3 and Y1 have the meaning cited in claim 1, and which can be used for treating tumours.
(FR)
Composés de formule I dans laquelle R, R1, R2, R3, R4, R5, R6, R7, R8, Z1, Z2, Z3 et Y1 possèdent la signification figurant à la revendication 1, qui peuvent être utilisés entre autres pour traiter des tumeurs.
Latest bibliographic data on file with the International Bureau