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1. WO2006096816 - HUMAN LEPTIN-DERIVED POLYPEPTIDES AND USES THEREOF

Publication Number WO/2006/096816
Publication Date 14.09.2006
International Application No. PCT/US2006/008503
International Filing Date 09.03.2006
IPC
C07K 14/575 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
575Hormones
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 15/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
A61P 3/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
04Anorexiants; Antiobesity agents
A61P 3/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
A61P 9/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
10for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applicants
  • THE UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM [US]/[US] (AllExceptUS)
  • ZHAO, Allan, Z. [US]/[US] (UsOnly)
Inventors
  • ZHAO, Allan, Z.
Agents
  • BENT, Stephen, A.
Priority Data
11/327,59606.01.2006US
60/659,75709.03.2005US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) HUMAN LEPTIN-DERIVED POLYPEPTIDES AND USES THEREOF
(FR) POLYPEPTIDES DERIVES DE LA LEPTINE HUMAINE ET LEURS UTILISATIONS
Abstract
(EN)
A polypeptide that contains an amino acid sequence present in human leptin blocks the inhibitory effect of human C-Reactive Protein on human leptin. Accordingly, such a polypeptide is implicated in an approach to treating or preventing conditions associated with the impact of CRP on leptin.
(FR)
L'invention concerne un polypeptide contenant une séquence d'acides aminés présente dans la leptine humaine et bloquant l'effet inhibiteur de la protéine C réactive (CRP) humaine sur la leptine humaine. Par conséquent, ce polypeptide est impliqué dans une approche visant à traiter ou prévenir des affections associées à l'effet de la CRP sur la leptine.
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