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1. WO2006096116 - METHOD OF STERILIZATION

Publication Number WO/2006/096116
Publication Date 14.09.2006
International Application No. PCT/SE2006/000284
International Filing Date 06.03.2006
IPC
A61L 2/18 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
16using chemical substances
18Liquid substances
B01D 15/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
15Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
G01N 30/00 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
30Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography
CPC
A61L 2/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
02using physical phenomena
04Heat
B01D 15/20
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
15Separating processes involving the treatment of liquids with solid sorbents
08Selective adsorption, e.g. chromatography
10characterised by constructional or operational features
20relating to the conditioning of the sorbent material
G01N 30/50
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
30Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography ; or field flow fractionation;
02Column chromatography
50Conditioning of the sorbent material or stationary liquid
Applicants
  • GE HEALTHCARE BIO-SCIENCES AB [SE]/[SE] (AllExceptUS)
  • BERGLÖF, Jan [SE]/[SE] (UsOnly)
  • DREVIN, Ingrid [SE]/[SE] (UsOnly)
  • LIND, Ola [SE]/[SE] (UsOnly)
  • SEGERBO, Ulf [SE]/[SE] (UsOnly)
Inventors
  • BERGLÖF, Jan
  • DREVIN, Ingrid
  • LIND, Ola
  • SEGERBO, Ulf
Agents
  • KILANDER, Annika
Priority Data
0500554-107.03.2005SE
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD OF STERILIZATION
(FR) PROCEDE DE STERILISATION
Abstract
(EN)
The present invention relates to a method of sterilizing a chromatography column which is packed with a separation matrix, which method comprises passing a super-heated aqueous liquid through the packing of the column to obtain at least one substantially sterile packed chromatography column. The method may also comprise a preceding heating. In the most advantageous embodiment, the superheated aqueous liquid is passed in a substantially uniform flow through the packing of the column, resulting in a sterility of the packed column.
(FR)
La présente invention concerne un procédé de stérilisation d'une colonne de chromatographie qui est garnie d'une matrice de séparation, ledit procédé consistant à envoyer un liquide aqueux chauffé à haute température dans la garniture de la colonne pour obtenir au moins une colonne de chromatographie garnie sensiblement stérile. Dans la forme de réalisation la plus intéressante, le liquide aqueux chauffé à haute température est envoyé dans la garniture de la colonne, sous forme d'un flux sensiblement uniforme, ce qui assure la stérilisation de la colonne garnie.
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