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1. WO2006096084 - METHODS FOR INTRADERMAL, TRANSDERMAL OR TRANSMUCOSAL DELIVERY OF BIOLOGICALLY ACTIVE SUBSTANCES

Publication Number WO/2006/096084
Publication Date 14.09.2006
International Application No. PCT/RU2005/000108
International Filing Date 11.03.2005
IPC
A61K 47/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
02Inorganic compounds
CPC
A61K 48/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A61K 9/0021
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
A61K 9/006
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0053Mouth and digestive tract, i.e. intraoral and peroral administration
006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
A61K 9/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
08Solutions
A61K 9/70
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases ; ; Films; Fibres of the matrix type containing drug;
Applicants
  • VADA CONSULTING LIMITED [GB]/[GB] (AllExceptUS)
  • POMYTKIN, Igor Anatolievich [RU]/[RU] (UsOnly)
  • SOLOVIEV, Sergey Pavlovich [RU]/[RU] (UsOnly)
Inventors
  • POMYTKIN, Igor Anatolievich
  • SOLOVIEV, Sergey Pavlovich
Agents
  • AGENCY OF INTELLECTUAL PROPERTY PROTECTION AND DEVLOPMENT ERMAKOVA, STOLIAROVA & ASSOCIATION
Priority Data
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS FOR INTRADERMAL, TRANSDERMAL OR TRANSMUCOSAL DELIVERY OF BIOLOGICALLY ACTIVE SUBSTANCES
(FR) METHODES RELATIVES A LA DISTRIBUTION INTRADERMIQUE, TRANSDERMIQUE OU TRANSMUCOSALE DE SUBSTANCES BIOLOGIQUEMENT ACTIVES
Abstract
(EN)
This invention relates to method for intradermal, transdermal or transmucosal delivering a biologically active substance to a mammal in need thereof, which method comprises a step of co-administering to said mammal with the biologically active substance an effective amount of an absorption enhancer, which is water comprising from about 99.760 to about 10 99.999% of light isotopologue 1H2160 and up to 100% of residual isotopologues 1H2170, 1H2180, 1H2H160, 1H2H170, 1H2H180, 2H2160, 2H2170, and 2H2180. Such biologically active substance is selected from the group consisting of drugs, physiologically active peptides, physiologically active proteins, glycoproteins, nucleic acid, nutrients, vitamins, and minerals.
(FR)
L’invention concerne une méthode de distribution intradermique, transdermique ou transmucosale de substances biologiquement actives aux mammifères qui en ont besoin, cette méthode comprend une étape d’administration simultanée audit mammifère de la substance biologiquement active et d’une quantité efficace d’un activateur d’absorption ; l’eau est cet améliorateur d’absorption qui comprend entre environ 99,760 et environ 1099,999 % d'isotopologue léger 1H2160 et jusqu’à 100 % de résidus isotopologues 1H2170, 1H2180, 1H2H160, 1H2H170, 1H2H180, 2H2160, 2H2170, et 2H2180. Une telle substance biologiquement active est sélectionnée dans le groupe comprenant les médicaments, les peptides physiologiquement actifs, les protéines physiologiquement actives, les glycoprotéines, les acides nucléiques, les nutriments, les vitamines et les minéraux.
Also published as
EP5789961
Latest bibliographic data on file with the International Bureau