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1. WO2006094247 - AMNIOTIC MEMBRANE EXTRACTS, COMPOSITIONS THEREOF, AND METHODS OF USE

Publication Number WO/2006/094247
Publication Date 08.09.2006
International Application No. PCT/US2006/007776
International Filing Date 02.03.2006
IPC
A61K 35/50 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
48Reproductive organs
50Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
CPC
A61K 35/50
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
48Reproductive organs
50Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
Applicants
  • TISSUETECH, INC. [US]/[US] (AllExceptUS)
  • TSENG, Scheffer, CG [US]/[US] (UsOnly)
  • TSENG, David, Y. [US]/[US] (UsOnly)
  • LI, Wei [CN]/[US] (UsOnly)
  • HE, Hua [CN]/[US] (UsOnly)
Inventors
  • TSENG, Scheffer, CG
  • TSENG, David, Y.
  • LI, Wei
  • HE, Hua
Agents
  • HOSTETLER, Michael, J.
Priority Data
60/657,39902.03.2005US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) AMNIOTIC MEMBRANE EXTRACTS, COMPOSITIONS THEREOF, AND METHODS OF USE
(FR) EXTRAITS DE MEMBRANE AMNIOTIQUE, COMPOSITIONS A BASE DE CEUX-CI, ET PROCEDES D'UTILISATION
Abstract
(EN)
The present invention relates to the prevention and reduction of scarring and inflammation by amniotic membrane extracts or compositions thereof. The invention also relates to the preparation of soluble and fractionated amniotic membrane extracts and the preparation of gels comprising the amniotic membrane extract for enhanced use and application. The invention further provides an extract composition of amniotic membrane that is effective in the prevention and reduction of scarring and inflammation by suppression of TGF-&bgr; activity. The invention further provides a method for reducing scarring and inflammation, and enhancing healing of wounds. The invention also provides purified lumican from human AM for the treatment of scarring and inflammation.
(FR)
La présente invention a trait à la prévention et la réduction de cicatrisation et d'inflammation par des extraits de membrane amniotique et des compositions à base de ceux-ci. L'invention a également trait à la préparation d'extraits de membrane amniotique solubles et fractionnés et la préparation de gels comprenant l'extrait de membrane amniotique pour une utilisation et une application améliorées. L'invention a trait en outre à une composition d'extraits de membrane amniotique qui est efficace dans la prévention et la réduction de cicatrisation et d'inflammation par la suppression de l'activité de TGF-bêta. L'invention a également trait à un procédé pour la réduction de cicatrisation et d'inflammation, et l'amélioration de la cicatrisation de lésions. Enfin, l'invention a trait à du lumicanne dérivé de membrane amniotique humain pour le traitement de cicatrisation et d'inflammation.
Also published as
EP6737006
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