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1. WO2006093978 - FLOW SWITCHING ON A MULTI-STRUCTURED MICROFLUIDIC CD (COMPACT DISC) USING CORIOLIS FORCE

Publication Number WO/2006/093978
Publication Date 08.09.2006
International Application No. PCT/US2006/007119
International Filing Date 28.02.2006
IPC
C12M 3/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
CPC
B01L 2300/0806
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0803Disc shape
0806Standardised forms, e.g. compact disc [CD] format
B01L 2300/0864
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0861Configuration of multiple channels and/or chambers in a single devices
0864comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
B01L 2400/0409
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2400Moving or stopping fluids
04Moving fluids with specific forces or mechanical means
0403specific forces
0409centrifugal forces
B01L 2400/0412
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2400Moving or stopping fluids
04Moving fluids with specific forces or mechanical means
0403specific forces
0409centrifugal forces
0412using additionally coriolis forces
B01L 2400/0622
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2400Moving or stopping fluids
06Valves, specific forms thereof
0622distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
B01L 3/50273
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
502with fluid transport, e.g. in multi-compartment structures
5027by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
50273characterised by the means or forces applied to move the fluids
Applicants
  • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US]/[US] (AllExceptUS)
  • ZOVAL, Jim V. [US]/[US] (UsOnly)
  • MADOU, Marc J. [BE]/[US] (UsOnly)
  • JIA, Guangyao [CN]/[US] (UsOnly)
  • KIM, Jitae [KR]/[US] (UsOnly)
  • KIDO, Horacio [US]/[US] (UsOnly)
Inventors
  • ZOVAL, Jim V.
  • MADOU, Marc J.
  • JIA, Guangyao
  • KIM, Jitae
  • KIDO, Horacio
Agents
  • DAVIDSON, Michael S.
Priority Data
60/657,76002.03.2005US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) FLOW SWITCHING ON A MULTI-STRUCTURED MICROFLUIDIC CD (COMPACT DISC) USING CORIOLIS FORCE
(FR) COMMUTATION DE FLUX DANS UN CD (DISQUE COMPACT) MICROFLUIDIQUE MULTI-STRUCTURE FAISANT INTERVENIR LA FORCE DE CORIOLIS
Abstract
(EN)
A microfluidic switching device includes a planar substrate having a central axis of rotation and a radially-oriented microchannel disposed in the planar substrate that terminates at a junction. In one aspect, the junction is formed as a double-layered junction in which an upstream portion is vertically offset from a downstream portion. In addition, the upstream portion has a smaller effective cross-sectional area than the downstream portion. First and second outlet chambers are coupled at one end to the junction. The device is rotated about the central axis in a clockwise direction so as to cause the fluid in the reservoir to flow into the first (right) outlet chamber or in a counter-clockwise direction so as to cause the fluid in the reservoir to flow into the second (left) outlet chamber.
(FR)
L'invention concerne un dispositif de commutation microfluidique qui comprend un substrat planaire présentant un axe de rotation central et un microcanal orienté dans le sens radial disposé dans le substrat planaire qui s'achève au niveau d'une jonction. Selon un aspect de l'invention, la jonction se présente sous forme de jonction à double couche dans laquelle une partie amont est décalée de manière verticale par rapport à une partie aval. En outre, la partie amont présente une section transversale effective de taille inférieure à celle de la partie aval. Une première et une deuxième chambre de sortie sont raccordées à la jonction au niveau d'une extrémité. Ledit dispositif est mis en rotation autour de l'axe central dans le sens des aiguilles d'une montre de façon à amener le fluide présent dans le réservoir à couler dans la première chambre de sortie (droite) ou dans le sens inverse des aiguilles d'une montre de façon à amener le fluide présent dans le réservoir à couler dans la deuxième chambre de sortie (gauche).
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