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1. WO2006093758 - MICROIMPLANTS FOR OCULAR ADMINISTRATION

Publication Number WO/2006/093758
Publication Date 08.09.2006
International Application No. PCT/US2006/006279
International Filing Date 22.02.2006
Chapter 2 Demand Filed 18.12.2006
IPC
A61F 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
9Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
CPC
A61F 2210/0004
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2210Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
0004bioabsorbable
A61F 9/0017
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
9Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
0008Introducing ophthalmic products into the ocular cavity or retaining products therein
0017implantable in, or in contact with, the eye, e.g. ocular inserts
A61K 9/0051
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0048Eye, e.g. artificial tears
0051Ocular inserts, ocular implants
A61K 9/204
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, tablets, ; discs, rods
2004Excipients; Inactive ingredients
2022Organic macromolecular compounds
2031obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
204Polyesters, e.g. poly(lactide-co-glycolide)
Applicants
  • ALLERGAN, INC. [US]/[US] (AllExceptUS)
  • NIVAGGIOLI, Thierry [US]/[US] (UsOnly)
  • WEBER, David, A. [US]/[US] (UsOnly)
Inventors
  • NIVAGGIOLI, Thierry
  • WEBER, David, A.
Agents
  • DONOVAN, Stephen
Priority Data
11/070,15801.03.2005US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MICROIMPLANTS FOR OCULAR ADMINISTRATION
(FR) MICRO-IMPLANTS POUR UNE ADMINISTRATION OCULAIRE
Abstract
(EN)
Implants and microimplants are provided comprising homogeneous mixtures of active ingredient and bioerodible polymer, including microimplant having diameters of (0.019) inches or less and which can be delivered to the eye using self-sealing methods. Methods of manufacturing the implants and microimplants are provided that yield batches of highly uniform implants and microimplants within vary narrow tolerance ranges.
(FR)
La présente invention concerne des implants et des micro-implants qui comprennent des mélanges homogènes d'un ingrédient actif et d'un polymère bioérodable, y compris des micro-implants ayant des diamètres de 0,019 pouces ou moins et qui peuvent être administrés dans l’œil en utilisant des procédés autoscellants. L’invention concerne également des procédés de fabrication des implants et des micro-implants qui produisent des lots d’implants et de micro-implants très uniformes dans des plages de tolérances très étroites.
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