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1. WO2006093651 - METHODS AND KIT FOR DIAGNOSING TICK BORNE ILLNESSES

Publication Number WO/2006/093651
Publication Date 08.09.2006
International Application No. PCT/US2006/004595
International Filing Date 08.02.2006
IPC
G01N 33/569 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
569for microorganisms, e.g. protozoa, bacteria, viruses
G01N 33/53 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
G01N 33/68 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
CPC
G01N 2333/20
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2333Assays involving biological materials from specific organisms or of a specific nature
195from bacteria
20from Spirochaetales (O), e.g. Treponema, Leptospira
G01N 2333/29
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2333Assays involving biological materials from specific organisms or of a specific nature
195from bacteria
29from Richettsiales (o)
G01N 2333/43556
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2333Assays involving biological materials from specific organisms or of a specific nature
435from animals; from humans
43504from invertebrates
43552from insects
43556from ticks
G01N 2333/44
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2333Assays involving biological materials from specific organisms or of a specific nature
435from animals; from humans
44from protozoa
G01N 2800/42
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
42Poisoning, e.g. from bites or stings
G01N 33/53
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
Applicants
  • IMMUNOSCIENCES LAB, INC. [US]/[US] (AllExceptUS)
  • VOJDANI, Aristo [US]/[US] (UsOnly)
Inventors
  • VOJDANI, Aristo
Agents
  • HART, Daniel
Priority Data
11/066,39925.02.2005US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND KIT FOR DIAGNOSING TICK BORNE ILLNESSES
(FR) PROCEDES ET ENSEMBLE POUR DIAGNOSTIQUER LES MALADIES TRANSMISES PAR LES TIQUES
Abstract
(EN)
ELISA, Western Blot, and a peptide-based ELISA were applied to clinical specimens from patients with clinical symptoms of tick borne diseases, including Lyme disease. Peptides from different components of Borrelia during different cycles, including peptides from outer surface protein, leukocyte function associated antigens, immunodominant antigens, variable major proteins, and peptides from decorin-binding proteins of Borrelial subspecies (B. sensu stricto. B. afzelii, B. garinii) were used. Antibodies against specific peptides from Babesia and Ehrlichia were also measured.
(FR)
On a appliqué ELISA, Western Blot et ELISA à base de peptides à des échantillons cliniques provenant de patients souffrant de symptômes cliniques de maladies transmises par les tiques, y compris la maladie de Lyme. On a utilisé des peptides provenant de différents composants de Borrelia pendant des cycles différents, y compris les peptides provenant de la protéine de surface externe, les antigènes associés à la fonction de leucocytes, les antigènes immunodominants, les protéines principales variables et les peptides provenant des protéines de liaison de décorine des sous-espèces Borrelia (B. sensu stricto, B. afzelii, B. garinii). On a également mesuré des anticorps dirigés contre des peptides déterminés provenant de Babesia et d'Ehrlichia.
Also published as
EP6720565
Latest bibliographic data on file with the International Bureau