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1. WO2006093114 - METHOD OF PRODUCING CHLOROGENIC ACID COMPOSITION

Publication Number WO/2006/093114
Publication Date 08.09.2006
International Application No. PCT/JP2006/303680
International Filing Date 28.02.2006
IPC
C07C 67/56 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
67Preparation of carboxylic acid esters
48Separation; Purification; Stabilisation; Use of additives
56by solid-liquid treatment; by chemisorption
C07C 69/732 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
69Esters of carboxylic acids; Esters of carbonic or haloformic acids
66Esters of carboxylic acids having esterified carboxyl groups bound to acyclic carbon atoms and having any of the groups OH, O-metal, -CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
73of unsaturated acids
732of unsaturated hydroxy carboxylic acids
A61K 31/216 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
215of carboxylic acids
216of acids having aromatic rings, e.g. benactizyne, clofibrate
A61P 9/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
12Antihypertensives
CPC
A61K 31/216
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
215of carboxylic acids
216of acids having aromatic rings, e.g. benactizyne, clofibrate
A61P 9/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
12Antihypertensives
C07C 67/56
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
67Preparation of carboxylic acid esters
48Separation; Purification; Stabilisation; Use of additives
56by solid-liquid treatment; by chemisorption
Applicants
  • 花王株式会社 KAO CORPORATION [JP]/[JP] (AllExceptUS)
  • 福田 昌弘 FUKUDA, Masahiro [JP]/[JP] (UsOnly)
  • 高橋 宏和 TAKAHASHI, Hirokazu [JP]/[JP] (UsOnly)
  • 小西 敦 KONISHI, Atsushi [JP]/[JP] (UsOnly)
Inventors
  • 福田 昌弘 FUKUDA, Masahiro
  • 高橋 宏和 TAKAHASHI, Hirokazu
  • 小西 敦 KONISHI, Atsushi
Agents
  • 特許業務法人アルガ特許事務所 THE PATENT CORPORATE BODY ARUGA PATENT OFFICE
Priority Data
2005-05531901.03.2005JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) METHOD OF PRODUCING CHLOROGENIC ACID COMPOSITION
(FR) PROCEDE DE PRODUCTION D’UNE COMPOSITION D’ACIDE CHLOROGENIQUE
(JA) クロロゲン酸類組成物の製造方法
Abstract
(EN)
It is intended to provide a method whereby a chlorogenic acid composition containing chlorogenic acids at a high concentration and having a reduced caffeine content can be obtained at a high yield. A method of producing a chlorogenic acid composition characterized by comprising adsorbing a water-soluble composition extracted from fresh or roasted coffee beans by a column packed with an adsorbent and then eluting by passing a 0.5 to 20 vol% aqueous solution of ethanol.
(FR)
La présente invention a pour objet de fournir un procédé grâce auquel une composition d’acide chlorogénique contenant des acides chlorogéniques à une concentration élevée et ayant une teneur en caféine réduite peut être obtenue avec un rendement élevé. L’invention fournit un procédé de production d’une composition d’acide chlorogénique, caractérisée en ce qu’il comprend l’adsorption d’une composition hydrosoluble extraite à partir de grains de café frais ou torréfiés dans une colonne remplie d’un adsorbant puis l’élution en faisant passer une solution aqueuse d’éthanol de 0,5 à 20 % en volume.
(JA)
 クロロゲン酸類を高濃度で含有し、カフェインを低減させたクロロゲン酸類組成物を高収率で得る方法を提供する。  生コーヒー豆又は焙煎コーヒー豆から抽出した水溶性組成物を、吸着剤が充填されたカラムに吸着させ、次いで0.5~20vol%のエタノール水溶液を通液して溶出させることを特徴とするクロロゲン酸類組成物の製造方法。
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