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1. (WO2006091666) METHODS AND COMPOSITIONS FOR TREATING CONDITIONS OF THE EYE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/091666    International Application No.:    PCT/US2006/006272
Publication Date: 31.08.2006 International Filing Date: 22.02.2006
IPC:
A61K 39/395 (2006.01), A61K 41/00 (2006.01), A61K 31/409 (2006.01)
Applicants: MASSACHUSETTS EYE AND EAR INFIRMARY [US/US]; 243 Charles Street, Boston, MA 02114 (US) (For All Designated States Except US).
GRAGOUDAS, Evangelos, S. [US/US]; (US) (For US Only).
POULAKI, Vassiliki [GR/US]; (US) (For US Only).
MILLER, Joan, W. [CA/US]; (US) (For US Only)
Inventors: GRAGOUDAS, Evangelos, S.; (US).
POULAKI, Vassiliki; (US).
MILLER, Joan, W.; (US)
Agent: WILSON, Daniel, A.; Goodwin Procter LLP, Exchange Place, Boston, MA 02109 (US)
Priority Data:
60/655,723 23.02.2005 US
Title (EN) METHODS AND COMPOSITIONS FOR TREATING CONDITIONS OF THE EYE
(FR) METHODES ET COMPOSITIONS DE TRAITEMENT D'ETATS DE L'OEIL
Abstract: front page image
(EN)Provided are methods and compositions for treating ocular conditions characterized by the presence of unwanted choroidal neovasculature, for example, neovascular age-related macular degeneration. The selectivity and sensitivity of, for example, a photodynamic therapy (PDT)-based approach can be enhanced by combining the PDT with an anti-FasL factor, for example, an anti-FasL neutralizing antibody.
(FR)L'invention porte sur des méthodes et compositions de traitement d'états de l'oeil caractérisés par la présence indésirable de néovasculatures choroïdales par exemple dues à la dégénérescence maculaire du grand âge. On peut par exemple augmenter la sélectivité et la sensibilité d'une thérapie photodynamique (PDT) en la combinant à un facteur anti FasL tel que par exemple un anticorps anti FasL neutralisateur.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)