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Machine translation
1. (WO2006091567) HYDROXYALKYL SUBSTITUTED IMIDAZOQUINOLINE COMPOUNDS AND METHODS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/091567    International Application No.:    PCT/US2006/006042
Publication Date: 31.08.2006 International Filing Date: 22.02.2006
IPC:
C07D 471/04 (2006.01), A61K 31/4162 (2006.01)
Applicants: COLEY PHARMACEUTICAL GROUP, INC. [US/US]; 93 Worcester Street, Suite 101, Wellesley , MA 02481 (US) (For All Designated States Except US).
KSHIRSAGAR, Tushar, A. [IN/US]; (US) (For US Only).
MERRILL, Bryon, A. [US/US]; (US) (For US Only).
NIWAS, Shri [US/US]; (US) (For US Only).
LUNDQUIST, Gregory, D., Jr. [US/US]; (US) (For US Only).
HEPPNER, Philip, D. [US/US]; (US) (For US Only).
DANIELSON, Michael, E. [US/US]; (US) (For US Only)
Inventors: KSHIRSAGAR, Tushar, A.; (US).
MERRILL, Bryon, A.; (US).
NIWAS, Shri; (US).
LUNDQUIST, Gregory, D., Jr.; (US).
HEPPNER, Philip, D.; (US).
DANIELSON, Michael, E.; (US)
Agent: GATES, Edward, R.; Wolf, Greenfield & Sacks, P.C., 600 Atlantic Avenue, Boston, MA 02210-2206 (US)
Priority Data:
60/655,495 23.02.2005 US
Title (EN) HYDROXYALKYL SUBSTITUTED IMIDAZOQUINOLINE COMPOUNDS AND METHODS
(FR) COMPOSES D'IMIDAZOQUINOLINES A SUBSTITUTION HYDROXYALKYLE ET PROCEDES
Abstract: front page image
(EN)Certain imidazoquinolines with a hydroxymethyl or hydroxyethyl substituent at the 2-position, and an aryl or heteroaryl substituent at the 7-position, pharmaceutical compositions containing the compounds, intermediates, methods of making and methods of use of these compounds as immunomodulators, for preferentially inducing IFN-&agr; biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
(FR)L'invention concerne certaines imidazoquinolines présentant un substituant hydroxyméthyle ou hydroxyéthyle à la position 2, et un substituant aryle ou hétéroaryle à la position 7, des compositions pharmaceutiques contenant lesdits composés, des intermédiaires, des procédés de préparation et des procédés d'utilisation desdits composés en tant qu'immunomodulateurs, afin d'induire préférentiellement une biosynthèse d'IFN-a chez des animaux, ainsi que dans le traitement de maladies, notamment des maladies virales et néoplasiques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)