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Machine translation
1. (WO2006090924) BLOCK COPOLYMER HAVING PEPTIDE LIGAND
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/090924    International Application No.:    PCT/JP2006/304202
Publication Date: 31.08.2006 International Filing Date: 28.02.2006
IPC:
C08G 69/08 (2006.01), A61K 47/42 (2006.01), C07K 2/00 (2006.01)
Applicants: THE UNIVERSITY OF TOKYO [JP/JP]; 3-1, Hongo 7-chome, Bunkyo-ku, Tokyo 1138654 (JP) (For All Designated States Except US).
KATAOKA, Kazunori [JP/JP]; (JP) (For US Only).
ITAKA, Keiji [JP/JP]; (JP) (For US Only).
NISHIYAMA, Nobuhiro [JP/JP]; (JP) (For US Only).
OBA, Makoto [JP/JP]; (JP) (For US Only).
FUKUSHIMA, Shigeto [JP/JP]; (JP) (For US Only).
KANAYAMA, Naoki [JP/JP]; (JP) (For US Only)
Inventors: KATAOKA, Kazunori; (JP).
ITAKA, Keiji; (JP).
NISHIYAMA, Nobuhiro; (JP).
OBA, Makoto; (JP).
FUKUSHIMA, Shigeto; (JP).
KANAYAMA, Naoki; (JP)
Agent: KOBAYASHI, Hiroshi; c/o ABE, IKUBO & KATAYAMA Fukuoka Bldg. 9th Fl. 8-7, Yaesu 2-chome Chuo-ku, Tokyo 1040028 (JP)
Priority Data:
2005-054260 28.02.2005 JP
Title (EN) BLOCK COPOLYMER HAVING PEPTIDE LIGAND
(FR) COPOLYMERE BLOC AYANT UN LIGAND PEPTIDIQUE
(JA) ペプチドリガンドを有するブロック共重合体
Abstract: front page image
(EN)Disclosed is a drug carrier having a target-directive property, specifically a gene carrier. A peptide block copolymer having an uncharged segment and a segment derived from a polyamino acid, the uncharged segment having a terminal end comprising a peptide ligand having a weight average molecular weight of 50 to 20,000.
(FR)L'invention présente un véhicule médicamenteux ayant une propriété d'orientation ciblée, précisément un véhicule génique. Elle concerne un copolymère bloc peptidique ayant un segment non chargé et un segment dérivé d'un acide polyaminé, le segment non chargé ayant une extrémité comprenant un ligand peptidique ayant un poids moléculaire moyen de 50 à 20 000.
(JA)本発明は、標的指向性が付与されたドラッグキャリアー、特に遺伝子キャリアーを提供することを課題とする。 非荷電性セグメントと、ポリアミノ酸由来のセグメントとを有するペプチドブロック共重合体であって、非荷電性セグメントの末端が重量平均分子量50~20,000のペプチドリガンドであるペプチドブロック共重合体により、上記課題を解決する。
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)