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1. (WO2006090264) A PROCESS FOR THE SYNTHESIS OF 2-AMINO-5-PROTECTED AMINO-3-HYDROXY-1, 6-DIPHENYLHEXANE OR A SALT THEREOF - AN INTERMEDIATE FOR ANTIVIRAL DRUGS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/090264    International Application No.:    PCT/IB2006/000417
Publication Date: 31.08.2006 International Filing Date: 28.02.2006
IPC:
C07C 271/20 (2006.01), C07C 213/00 (2006.01), C07C 269/04 (2006.01), C07D 239/10 (2006.01), C07D 277/28 (2006.01)
Applicants: RANBAXY LABORATORIES LIMITED [IN/IN]; Plot No. 90, Sector - 32, Gurgaon, Haryana 122 001 (IN) (For All Designated States Except US).
BOSE, Prosenjit [IN/IN]; (IN) (For US Only).
BISWAS, Sujoy [IN/IN]; (IN) (For US Only).
RATHORE, Ramendra, Singh [IN/IN]; (IN) (For US Only).
SACHDEVA, Yoginder, Pal [IN/IN]; (IN) (For US Only).
KUMAR, Yatendra [IN/IN]; (IN) (For US Only)
Inventors: BOSE, Prosenjit; (IN).
BISWAS, Sujoy; (IN).
RATHORE, Ramendra, Singh; (IN).
SACHDEVA, Yoginder, Pal; (IN).
KUMAR, Yatendra; (IN)
Common
Representative:
RANBAXY LABORATORIES LIMITED; c/o DESHMUKH, Jay R., 600 College Road East, Suite 2100, Princeton, NJ 08540 (US)
Priority Data:
430/DEL/2005 28.02.2005 IN
Title (EN) A PROCESS FOR THE SYNTHESIS OF 2-AMINO-5-PROTECTED AMINO-3-HYDROXY-1, 6-DIPHENYLHEXANE OR A SALT THEREOF - AN INTERMEDIATE FOR ANTIVIRAL DRUGS
(FR) PROCEDE DE SYNTHESE DE 2-AMINO-5- AMINO PROTEGE-3-HYDROXY-1, 6-DIPHENYLHEXANE OU UN SEL DE CELUI-CI UN INTERMEDIAIRE POUR MEDICAMENTS ANTIVIRAUX
Abstract: front page image
(EN)The present invention relates to an improved process for preparing 2-amino-5-protected-amino-3-hydroxy-1,6-diphenylhexane compounds or acid addition salts thereof, which can be useful intermediates for preparing compounds with antiviral activity. The present invention further provides a process for preparing HIV protease inhibitors, lopinavir and ritonavir.
(FR)L'invention concerne un procédé amélioré permettant de préparer des composés 2-amino-5-amino protégé-3-hydroxy-1,6-diphénylehexane ou des sels d'addition d'acide de ceux-ci, que l'on peut utiliser comme intermédiaires permettant de préparer des composés à activité antivirale. L'invention concerne également un procédé de préparation d'inhibiteurs de protéase de VIH, lopinavir et ritonavir.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)