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1. (WO2006089700) PYRROLIDINE AND PIPERIDINE ACETYLENE DERIVATIVES FOR USE AS MGLUR5 ANTAGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/089700    International Application No.:    PCT/EP2006/001505
Publication Date: 31.08.2006 International Filing Date: 20.02.2006
IPC:
C07D 405/06 (2006.01), C07D 211/48 (2006.01), C07D 413/06 (2006.01), C07D 401/06 (2006.01), C07D 471/04 (2006.01), C07D 405/14 (2006.01), C07D 403/06 (2006.01), A61K 31/445 (2006.01), A61K 31/40 (2006.01), A61P 25/00 (2006.01), A61P 29/00 (2006.01)
Applicants: NOVARTIS AG [CH/CH]; Lichtstrasse 35, CH-4056 Basel (CH) (AE, AG, AL, AM, AU, AZ, BA, BB, BE, BF, BG, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GW, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, MG, MK, ML, MN, MR, MW, MX, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, YU, ZA, ZM, ZW only).
NOVARTIS PHARMA GMBH [AT/AT]; Brunner Strasse 59, A-1230 Vienna (AT) (AT only).
GLATTHAR, Ralf [DE/DE]; (DE) (For US Only).
TROXLER, Thomas, J. [CH/CH]; (CH) (For US Only).
ZOLLER, Thomas [FR/FR]; (FR) (For US Only).
NOZULAK, Joachim [DE/DE]; (DE) (For US Only)
Inventors: GLATTHAR, Ralf; (DE).
TROXLER, Thomas, J.; (CH).
ZOLLER, Thomas; (FR).
NOZULAK, Joachim; (DE)
Agent: DE WEERD, Peter; Novartis AG, Corporate Intellectual Property, CH-4002 Basel (CH)
Priority Data:
0503646.2 22.02.2005 GB
Title (EN) PYRROLIDINE AND PIPERIDINE ACETYLENE DERIVATIVES FOR USE AS MGLUR5 ANTAGONISTS
(FR) DÉRIVÉS D'ACÉTYLÈNE DE LA PYRROLIDINE ET DE LA PIPÉRIDINE POUR UTILISATION COMME ANTAGONISTES DE MGLUR5
Abstract: front page image
(EN)The invention provides Compounds of formula (I) wherein the substituents are as defined in the description, processes and intermediates for their preparation and their use as pharmaceuticals in the treatment of disorders mediated by mGluR5.
(FR)La présente invention concerne des composés de la formule (I), où les substituants sont définis comme dans la description, des procédés et des intermédiaires pour leur préparation et leur utilisation comme produits pharmaceutiques dans le traitement de désordres induits par mGluR5.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)