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1. WO2006089067 - BORON-CONTAINING SMALL MOLECULES

Publication Number WO/2006/089067
Publication Date 24.08.2006
International Application No. PCT/US2006/005542
International Filing Date 16.02.2006
Chapter 2 Demand Filed 12.07.2006
IPC
A61K 31/343 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
34having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
343condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
C07D 307/77 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
307Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
77ortho- or peri-condensed with carbocyclic rings or ring systems
CPC
A61K 31/69
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
69Boron compounds
A61K 31/70
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
A61K 31/7076
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7052having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
706containing six-membered rings with nitrogen as a ring hetero atom
7064containing condensed or non-condensed pyrimidines
7076containing purines, e.g. adenosine, adenylic acid
A61K 9/0012
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 15/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
Applicants
  • ANACOR PHARMACEUTICALS, INC. [US]/[US] (AllExceptUS)
  • BAKER, Stephen, J. [GB]/[US] (UsOnly)
  • AKAMA, Tsutomu [JP]/[US] (UsOnly)
  • BELLINGER-KAWAHARA, Carolyn [US]/[US] (UsOnly)
  • HERNANDEZ, Vincent, S. [US]/[US] (UsOnly)
  • HOLD, Karin, M. [US]/[US] (UsOnly)
  • LEYDEN, James, J. [US]/[US] (UsOnly)
  • MAPLES, Kirk, R. [US]/[US] (UsOnly)
  • PLATTNER, Jacob, J. [US]/[US] (UsOnly)
  • SANDERS, Virginia [US]/[US] (UsOnly)
  • ZHANG, Yong-Kang [US]/[US] (UsOnly)
Inventors
  • BAKER, Stephen, J.
  • AKAMA, Tsutomu
  • BELLINGER-KAWAHARA, Carolyn
  • HERNANDEZ, Vincent, S.
  • HOLD, Karin, M.
  • LEYDEN, James, J.
  • MAPLES, Kirk, R.
  • PLATTNER, Jacob, J.
  • SANDERS, Virginia
  • ZHANG, Yong-Kang
Agents
  • ESKER, Todd
Priority Data
60/654,06016.02.2005US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BORON-CONTAINING SMALL MOLECULES
(FR) PETITES MOLECULES CONTENANT DU BORE
Abstract
(EN)
This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
(FR)
L'invention concerne des composés servant à traiter des infections fongiques, plus particulièrement à assurer un traitement topique pour une onychomycose et/ou des infections fongiques cutanées. L'invention concerne des composés actifs contre les champignons et qui présentent des propriétés leur permettant, lorsqu'ils sont mis en contact avec un patient, d'atteindre la partie spécifique de la peau, des ongles, des poils, des pattes ou des sabots infectée par le champignon. Les composés de l'invention présentent en particulier des propriétés physiochimiques qui facilitent la pénétration dans la plaque unguéale.
Latest bibliographic data on file with the International Bureau