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Pub. No.:    WO/2006/089067    International Application No.:    PCT/US2006/005542
Publication Date: 24.08.2006 International Filing Date: 16.02.2006
Chapter 2 Demand Filed:    12.07.2006    
A61K 31/343 (2006.01), C07D 307/77 (2006.01)
Applicants: ANACOR PHARMACEUTICALS, INC. [US/US]; 1060 East Meadow Circle, Palo Alto, CA 94303-4230 (US) (For All Designated States Except US).
BAKER, Stephen, J. [GB/US]; (US) (For US Only).
AKAMA, Tsutomu [JP/US]; (US) (For US Only).
BELLINGER-KAWAHARA, Carolyn [US/US]; (US) (For US Only).
HERNANDEZ, Vincent, S. [US/US]; (US) (For US Only).
HOLD, Karin, M. [US/US]; (US) (For US Only).
LEYDEN, James, J. [US/US]; (US) (For US Only).
MAPLES, Kirk, R. [US/US]; (US) (For US Only).
PLATTNER, Jacob, J. [US/US]; (US) (For US Only).
SANDERS, Virginia [US/US]; (US) (For US Only).
ZHANG, Yong-Kang [US/US]; (US) (For US Only)
Inventors: BAKER, Stephen, J.; (US).
AKAMA, Tsutomu; (US).
HERNANDEZ, Vincent, S.; (US).
HOLD, Karin, M.; (US).
LEYDEN, James, J.; (US).
MAPLES, Kirk, R.; (US).
PLATTNER, Jacob, J.; (US).
SANDERS, Virginia; (US).
ZHANG, Yong-Kang; (US)
Agent: ESKER, Todd; MORGAN LEWIS & BOCKIUS LLP, 2 Palo Alto Square, 3000 El Camino Real, Suite 700, Palo Alto, CA 94306 (US)
Priority Data:
60/654,060 16.02.2005 US
Abstract: front page image
(EN)This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
(FR)L'invention concerne des composés servant à traiter des infections fongiques, plus particulièrement à assurer un traitement topique pour une onychomycose et/ou des infections fongiques cutanées. L'invention concerne des composés actifs contre les champignons et qui présentent des propriétés leur permettant, lorsqu'ils sont mis en contact avec un patient, d'atteindre la partie spécifique de la peau, des ongles, des poils, des pattes ou des sabots infectée par le champignon. Les composés de l'invention présentent en particulier des propriétés physiochimiques qui facilitent la pénétration dans la plaque unguéale.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)