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1. (WO2006089062) DETECTION OF BIOMARKERS FOR NEUROPSYCHIATRIC DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/089062    International Application No.:    PCT/US2006/005533
Publication Date: 24.08.2006 International Filing Date: 15.02.2006
IPC:
C12Q 1/68 (2006.01), A61K 38/17 (2006.01)
Applicants: REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO [US/US]; 1111 Franklin Street, Fifth Floor, Oakland, California 94607-5200 (US) (For All Designated States Except US).
TSUANG, Ming, T. [US/US]; (US) (For US Only).
EVERALL, Ian, P. [US/US]; (US) (For US Only).
GLATT, Stephen, J. [US/US]; (US) (For US Only).
KREMEN, William, S. [US/US]; (US) (For US Only)
Inventors: TSUANG, Ming, T.; (US).
EVERALL, Ian, P.; (US).
GLATT, Stephen, J.; (US).
KREMEN, William, S.; (US)
Agent: MCCRACKIN, Ann, M.; Schwegman, Lundberg, Woessner & Kluth, P.A., P. O. Box 2938, Minneapolis, Minnesota 55402 (US)
Priority Data:
60/653,217 15.02.2005 US
Title (EN) DETECTION OF BIOMARKERS FOR NEUROPSYCHIATRIC DISORDERS
(FR) DETECTION DE BIOMARQUEURS CORRESPONDANT A DES TROUBLES NEUROPSYCHIATRIQUES
Abstract: front page image
(EN)Systems and methods provide a comprehensive high-throughput approach toward the sequential identification, prioritization, verification, and validation of etiologic factors in neuropsychiatric disorders, some of which can also be utilized as biomarkers for these illnesses. The systems and methods determine patterns of gene expression in various tissues from various samples under various experimental and non-experimental conditions, and uses the differences and similarities between the gene expression profiles observed under these conditions to delineate distinct gene expression profiles of risk and treatment of neuropsychiatric disorders.
(FR)La présente invention concerne des systèmes et procédés offrant une puissante approche globale pour l'identification séquentielle, la priorisation, la vérification et la validation de facteurs étiologiques dans le cadre de troubles neuropsychiatriques, certains d'entre eux pouvant également convenir comme biomarqueurs de ces maladies. Ces systèmes et procédés, qui permettent de déterminer des profils d'expression génique dans des tissus à partir d'échantillons dans des conditions expérimentales et non expérimentales, utilisent les différences et similitudes entre les profils d'expressions géniques observés dans ces conditions pour délimiter les profils de risques d'expressions géniques distinctes et le traitement de ces troubles neuropsychiatriques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)