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Machine translation
1. (WO2006089009) METHODS AND COMPOSITIONS FOR THE TREATMENT OF LIPID-ASSOCIATED DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2006/089009    International Application No.:    PCT/US2006/005450
Publication Date: 24.08.2006 International Filing Date: 15.02.2006
Chapter 2 Demand Filed:    20.12.2006    
IPC:
G01N 33/566 (2006.01), A61K 31/443 (2006.01)
Applicants: ARENA PHARMACEUTICALS, INC. [US/US]; 6166 Nancy Ridge Drive, San Diego, CA 92129 (US) (For All Designated States Except US).
KANEMITSU-PARKS, Martha [US/US]; (US) (For US Only).
RICHMAN, Jeremy, G. [US/US]; (US) (For US Only).
MACIEJEWSKI-LENOIR, Dominique [US/US]; (US) (For US Only).
CONNOLLY, Daniel. T. [US/US]; (US) (For US Only)
Inventors: KANEMITSU-PARKS, Martha; (US).
RICHMAN, Jeremy, G.; (US).
MACIEJEWSKI-LENOIR, Dominique; (US).
CONNOLLY, Daniel. T.; (US)
Agent: GODDARD, Christine, A.; Fish & Richardson P.C., P.O. Box 1022, Minneapolis, MN 55440-1022 (US)
Priority Data:
60/654,684 18.02.2005 US
Title (EN) METHODS AND COMPOSITIONS FOR THE TREATMENT OF LIPID-ASSOCIATED DISORDERS
(FR) PROCEDES ET COMPOSITIONS POUR LE TRAITEMENT DE TROUBLES ASSOCIES AUX LIPIDES
Abstract: front page image
(EN)The invention provides a method of identifying a niacin receptor modulator with reduced flushing effect compared to niacin or a niacin analog, comprising determining the MAP kinase activity of said modulator, wherein a decrease in MAP kinase activity induced by said modulator compared to MAP kinase activity induced by niacin or a niacin analog indicates that said modulator has reduced flushing effect when compared to niacin or a niacin analog.
(FR)Procédé d'identification de modulateur de récepteur de niacine avec effet de rinçage réduit par rapport à la niacine ou à un analogue de niacine qui consiste à déterminer l'activité MAP kinase du modulateur, sachant qu'une baisse de l'activité en question induite par le modulateur par rapport à l'activé induite par la niacine ou un analogue de niacine indique que le modulateur a un effet de rinçage réduit par rapport à la niacine ou à un analogue de niacine
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SM, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)